Results 211 to 220 of about 70,786 (313)

One‐Step Glycoengineering of NK Cells With High‐Affinity Siglec Ligands for Cancer Immunotherapy

Advanced Science, Volume 13, Issue 26, 8 May 2026.
This study develops an engineered NmCSS enzyme with improved activity for bulky group modified sialic acids, enabling efficient synthesis of structurally diverse sialoside analogs in a single step. Glycan microarray screening identified Siglec high‐affinity ligands, which were incorporated onto natural killer (NK) cells via a one‐pot enzymatic system ...
Shuai Hu, Ben Huang, Lingyan Wang, Qiang Guo, Cuiping Jiang, Ruicheng Qi, Shuyao Wang, Lin‐Tai Da, Wenjie Peng   +8 more
wiley   +1 more source

NXPE1 alters the sialoglycome by acetylating sialic acids in the human colon. [PDF]

Nat Commun
Lee BS, Cook A, Sur S, Dobbyn L, Popoli M, Khalili S, Zhou S, Bettegowda C, Papadopoulos N, Gabrielson K, Buckhaults P, Vogelstein B, Kinzler KW, Wyhs N.   +13 more
europepmc   +1 more source

The role of cell surface sialic acids for SARS-CoV-2 infection. [PDF]

Glycobiology, 2021
Sun XL.
europepmc   +1 more source

Variety of sialic acids occurring in the bovine sublingual gland.

, 1994
D Accili, María Gabriella Gabrielli, G Menghi   +2 more
openalex   +1 more source

Effect Of Removing Sialic Acid From Vascular Endothelium In Living Animals On Its Interaction With Circulating Platelets [PDF]

, 1981
Gabriele Born, P. Görög, Ingrid U. Schraufstätter   +2 more
openalex   +1 more source

SIRT1 Prevents Ferroptosis in Corneal Epithelial Cells by Enhancing HIF1α Protein Stability in Dry Eye Disease

Advanced Science, Volume 13, Issue 26, 8 May 2026.
Hyperosmotic stress drives ferroptosis in corneal epithelium via SIRT1 downregulation. This work demonstrates that SIRT1 activation stabilizes HIF1α, which transcriptionally upregulates GPX4 to inhibit lipid peroxidation and cell death. The identified SIRT1/HIF1α/GPX4 axis reveals a novel defense mechanism and potential therapy for dry eye disease ...
Lili Lian, Zhenmin Le, Xuanqiao Ye, Zimo Wang, Jiuxiao Li, Chenyu Dong, Yetao Shen, Jiazheng Li, Yueping Ren, Xiaoyin Ma, Wei Chen, Qinxiang Zheng   +11 more
wiley   +1 more source

Increased levels of α2-3- and α2-6-linked sialic acids during airway inflammation govern influenza A binding to peripheral airway mucins in a subtype-dependent manner. [PDF]

Front Immunol
Benktander J, Hayashi MPQ, Nordén R, Pettersson L, Paulsson M, Lindén A, Lindén SK.   +6 more
europepmc   +1 more source

Sialic acids in gynecological cancer development and progression: Impact on diagnosis and treatment. [PDF]

Int J Cancer, 2022
Berghuis AY, Pijnenborg JFA, Boltje TJ, Pijnenborg JMA.   +3 more
europepmc   +1 more source

Sialic Acid Content And The Biological Activity Of Stuart Factor (F X) [PDF]

, 1981
Alfred M. Engel
openalex   +1 more source

Advanced Non‐Enzymatic Electrochemical Sensor Materials for Alzheimer's Disease Biomarkers

Analysis &Sensing, Volume 6, Issue 3, May 2026.
This review summarizes advances in materials‐driven, non‐enzymatic electrochemical biosensors for early Alzheimer's diagnosis via biofluid analysis. Amyloid‐β and hyperphosphorylated Tau are highlighted alongside sensor performance metrics, including sensitivity and selectivity.
Wei‐Ting Ting, Md Younus Ali, Claire Gage, Margaret Fahnestock, M. Firoz Mian, Matiar M. R. Howlader   +5 more
wiley   +1 more source