Results 241 to 250 of about 69,641 (328)
Studies on the Stability of Simple Derivatives of Sialic Acid
, 1964 John D. Karkas, Erwin Chargaff
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International Journal of Cancer, Volume 157, Issue 9, Page 1948-1962, 1 November 2025.What's new? Our research highlights how tumor sialylation affects tumor growth and reshapes the immune tumor microenvironment in colorectal cancer. We demonstrate for the first time that complete removal of sialic acids from colorectal tumor cells elicits a robust anti‐tumor immune response, but does not enhance anti‐PD‐L1 blockade efficacy.
Irene van der Haar Àvila +11 more
wiley +1 more source
ALTERATIONS IN SIALIC ACID IN THE EPIDIDYMIS OF THE PUBERAL RAT IN RESPONSE TO CHANGES IN FUNCTIONAL ACTIVITY OF THE TESTIS [PDF]
, 1971 M. Rajalakshmi, M.R.N. Prasad
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Trial Readiness: Understanding the Natural History of Rare Diseases
Journal of Inherited Metabolic Disease, Volume 48, Issue 6, November 2025.ABSTRACT Inherited metabolic diseases (IMD) represent the largest and still growing group of treatable genetic disorders and are increasingly amenable to targeted interventions that achieve varying degrees of prognostic improvement. Innovative therapies are on the horizon and offer promising opportunities for disease‐changing treatment for a variety of
Thomas Opladen +6 more
wiley +1 more source
Protein Science, Volume 34, Issue 11, November 2025.Abstract Uridine diphosphate N‐acetylglucosamine (UDP‐GlcNAc) 2‐epimerase (GNE)/N‐acetylmannosamine kinase is the rate‐limiting enzyme in sialic acid biosynthesis and a promising therapeutic target. We applied mass photometry (MP) to investigate GNE oligomerization and its modulation by three small‐molecule inhibitors (C5, C13, and C15).
Nico Boback +4 more
wiley +1 more source
Studies on Sialic Acid (Neuraminic Acid) in Cerebrospinal Fluid
, 1962 Akira Mukai, Tatsunori Ejima
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VARIATIONS IN THE SIALIC ACID CONCENTRATION OF GLOMERULAR BASEMENT MEMBRANE PREPARATIONS OBTAINED BY ULTRASONIC TREATMENT [PDF]
, 1970 Steven C. Mohos, L Skoza
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Precursor of H-type II histo-blood group antigen and subterminal sialic acids on gangliosides are significantly implicated in cell entry and infection by a porcine P[11] rotavirus. [PDF]
Emerg Microbes InfectYan M +8 more
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Role of sialic acid in erythrocyte survival [PDF]
, 1975 JR Durocher, RC Payne, Conrad Me
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