Results 1 to 10 of about 5,594 (243)

Sialoglycoproteins and N-Glycans from Secreted Exosomes of Ovarian Carcinoma Cells [PDF]

PLoS ONE, 2013
Exosomes consist of vesicles that are secreted by several human cells, including tumor cells and neurons, and they are found in several biological fluids.
Conradt, Harald S., Costa, Júlia, Escrevente, Cristina, Grammel, Nicolas, Kandzia, Sebastian, Tranfield, Erin M., Zeiser, Johannes   +6 more
core   +8 more sources

Transdermal characteristic study of bovine sialoglycoproteins with anti-skin aging and accelerating skin wound healing. [PDF]

J Cosmet Dermatol
Abstract Background Sialoglycoproteins play important roles in various biological processes, including cell adhesion, immune response, and cell signaling. Our previous studies indicated that the bovine sialoglycoproteins could be developed as a reagent against skin aging and as a new candidate for accelerating skin wound healing as well as inhibiting ...
Cheng H, Li X, Du J, Dang L, Wang S, Ding L, Zhang F, Sun S, Li Z.   +8 more
europepmc   +2 more sources

Comparative Analysis of HMC3 and C20 Microglial Cell Lines Reveals Differential Myeloid Characteristics and Responses to Immune Stimuli. [PDF]

Immunology
This study highlights comparative proteomic and morphological analyses of HMC3 and C20 microglial cell lines under baseline and inflammatory stimuli (LPS and IFN‐γ). Despite a 76.6% similarity in proteins, unstimulated HMC3 showed a transcriptional cell protein profile, whereas unstimulated C20 had a cell protein profile associated with the immune ...
Gunasegaran B, Krishnamurthy S, Chow SS, Villanueva MD, Guller A, Ahn SB, Heng B.   +6 more
europepmc   +2 more sources

Roles of bovine sialoglycoproteins for anti‐skin aging and accelerating skin wound healing

Journal of Cosmetic Dermatology, Volume 22, Issue 12, Page 3470-3479, December 2023., 2023
Abstract Background Fibroblasts are the most predominant cell subpopulation in the dermal layer of human skin, they play an important role in maintaining skin architecture and function. The senescence of fibroblasts is one of major causes of skin aging and chronic wound in the elderly, which is accompanied with a reduction of α2,6‐sialylation on the ...
Xilong Wang, Lixin Yue, Fan Zhang, Xiaojuan Bao, Wanghua Song, Zheng Li   +5 more
wiley   +1 more source

Diversity of sialic acids and sialoglycoproteins in gametes and at fertilization

Frontiers in Cell and Developmental Biology, 2022
Sialic acids are a family of 9-carbon monosaccharides with particular physicochemical properties. They modulate the biological functions of the molecules that carry them and are involved in several steps of the reproductive process. Sialoglycoproteins participate in the balance between species recognition and specificity, and the mechanisms of these ...
Fliniaux, Ingrid, Marchand, Guillaume, Molinaro, Caroline, Decloquement, Mathieu, Martoriati, Alain, Marin, Matthieu, Bodart, Jean-Francois, Harduin Lepers, Anne, Cailliau, Katia   +8 more
openaire   +5 more sources

TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5

Advanced Science, Volume 10, Issue 25, September 5, 2023., 2023
Tumor protein 53 regulating kinase (TP53RK) is positively correlated to renal dysfunction and fibrosis in chronic kidney disease (CKD). Deleting TP53RK in renal tubule or fibroblasts mitigates renal fibrosis. Mechanically, TP53RK phosphorylates baculoviral IAP repeat containing 5(Birc5) to promote partial epithelial‐mesenchymal transition in renal ...
Mengqiu Wu, Qianqian Jin, Xinyue Xu, Jiaojiao Fan, Weiyi Chen, Mengqiu Miao, Ran Gu, Shengnan Zhang, Yan Guo, Songming Huang, Yue Zhang, Aihua Zhang, Zhanjun Jia   +12 more
wiley   +1 more source

Recommendations for intervertebral disc notochordal cell investigation: From isolation to characterization

JOR SPINE, Volume 6, Issue 3, September 2023., 2023
To date, there is a lack of consensus for the extraction, numeration, in vitro culture, and characterization of intervertebral disc notochordal cells (NCs). With large variations in methodological approaches affecting progress in this field. Thus, this article aims to provide key recommendations and methodologies for NC isolation, numeration, in vitro ...
Rebecca J. Williams, Lisanne T. Laagland, Frances C. Bach, Lizzy Ward, Wilson Chan, Vivian Tam, Adel Medzikovic, Shaghayegh Basatvat, Lily Paillat, Nicolas Vedrenne, Joseph W. Snuggs, Deepani W. Poramba‐Liyanage, Judith A. Hoyland, Danny Chan, Anne Camus, Stephen M. Richardson, Marianna A. Tryfonidou, Christine L. Le Maitre   +17 more
wiley   +1 more source

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2019–2020

Mass Spectrometry Reviews, Volume 42, Issue 5, Page 1984-2206, September/October 2023., 2023
Abstract This review is the tenth update of the original article published in 1999 on the application of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry to the analysis of carbohydrates and glycoconjugates and brings coverage of the literature to the end of 2020.
David J. Harvey
wiley   +1 more source

Swine influenza virus strains recognize sialylsugar chains containing the molecular species of sialic acid predominantly present in the swine tracheal epithelium [PDF]

, 1997
We determined the ratio of N-glycolylneuraminic acid (Neu5Gc) to N-acetylneuraminic acid (Neu5Ac) in swine respiratory epithelia by fluorometric high-performance liquid chromatography, and examined the binding specificity of swine influenza virus strains
Horiike, Goh, Ito, Toshihiro, Kawabe, Kaoru, Kawaoka, Yoshihiro, Kida, Hiroshi, Masuda, Hiroyuki, Matsuda, Masao, Miyamoto, Daisei, Nishimura, Shin-Ichiro, Suzuki, Takashi, Suzuki, Yasuo, Yamagata, Tatsuya, Yamazaki, Yasuhiro   +12 more
core   +1 more source

Mechanism of Acyl Group Migration in Carbohydrates

Chemistry – A European Journal, Volume 29, Issue 43, August 1, 2023., 2023
Acyl groups are prone to migrate in carbohydrates, causing issues in the laboratory setting. Migration could also have biological relevance, such as in regulation of cell signaling. Recently, deeper investigations have been performed on the mechanism of this phenomenon.
Robert Lassfolk, Reko Leino
wiley   +1 more source