Genomic, Proteomic, and Phenotypic Spectrum of Novel O-Sialoglycoprotein Endopeptidase Variant in Four Affected Individuals With Galloway-Mowat Syndrome [PDF]
Galloway-Mowat syndrome is a rare autosomal recessive disease characterized by a unique combination of renal and neurological manifestations, including early-onset steroid-resistant nephrotic syndrome, microcephaly, psychomotor delay, and gyral ...
Malak Ali Alghamdi +25 more
doaj +2 more sources
Sialoglycoproteins and N-glycans from secreted exosomes of ovarian carcinoma cells. [PDF]
Exosomes consist of vesicles that are secreted by several human cells, including tumor cells and neurons, and they are found in several biological fluids.
Cristina Escrevente +6 more
doaj +6 more sources
Simple Binding and Dissociation of a Sialoglycoprotein Using Boronic Acid-Modified Functional Interfaces on Microparticles [PDF]
An overexpression of sialic acid is an indicator of metastatic cancer, and selective detection of sialic acid shows potential for cancer diagnosis. Boronic acid is a promising candidate for this purpose because of its ability to specifically bind to ...
Yukichi Horiguchi +4 more
doaj +2 more sources
Scrapie PrP 27-30 is a sialoglycoprotein [PDF]
The major scrapie prion protein, designated PrP 27-30, exhibited both charge and size heterogeneity after purification from infected hamster brains. Eight or more discrete charge isomers of PrP 27-30 with isoelectric points ranging from approximately pH 4.6 to 7.9 were found by using non-equilibrium pH gradient electrophoresis in the first dimension ...
D C, Bolton, R K, Meyer, S B, Prusiner
openaire +3 more sources
Evaluation of podoplanin expression in vulvar squamous cell carcinoma and stromal fibroblasts and its prognostic implications [PDF]
Although the immunohistochemical expression of the transmembrane sialoglycoprotein podoplanin (D2-40) has been repeatedly reported as a factor of prognosis in various tumor entities—its potential prognostic relevance in squamous cell carcinomas of the ...
Gilbert Georg Klamminger +11 more
doaj +2 more sources
Serum Podocalyxin Level as a Potential Biomarker for Diagnosis of Nephrotic Syndrome and Prediction of Steroid Response [PDF]
Objective: Idiopathic nephrotic syndrome (NS) is a common pediatric glomerular disorder. Podocyte damage constitutes a central mechanism in its pathophysiology.
Emre LEVENTOGLU +2 more
doaj +2 more sources
Podocalyxin and ciliary neurotrophic factor receptor are novel components of the surfaceome of chondrogenic cells [PDF]
Background Osteoarthritis is a degenerative joint disease characterized by progressive loss of articular cartilage and limited capacity for intrinsic repair.
Patrik Kovács +10 more
doaj +2 more sources
Binding of Transmissible Gastroenteritis Coronavirus to Cell Surface Sialoglycoproteins [PDF]
ABSTRACT The surface glycoprotein S of transmissible gastroenteritis virus (TGEV) has two binding activities. (i) Binding to porcine aminopeptidase N (pAPN) is essential for the initiation of infection. (ii) Binding to sialic acid residues on glycoproteins is dispensable for the infection of cultured cells but is required for ...
Christel, Schwegmann-Wessels +4 more
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Biochemistry and Oncology of Sialoglycoproteins [PDF]
Sialoglycoproteins are defined as proteins containing one or more sialyl oligosaccharides covalently bound via their reducing end to the polypeptide chain. Most, but not all, of the glycosylated proteins in animals contain sialic acid and therefore qualify as sialoglycoproteins.
Veer P. Bhavanandan, Kiyoshi Furukawa
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Studies on sialoglycoprotein complexes of human erythrocyte membranes [PDF]
R W, Stoddart, S M, Metcalfe
openaire +4 more sources

