The use of monoclonal antibodies to quantify the levels of sialoglycoproteins α and δ and variant sialoglycoproteins in human erythrocyte membranes [PDF]
By using radioiodinated monoclonal antibodies we have estimated that there are about 600 000 copies of sialoglycoprotein alpha (synonym glycophorin A) and 80 000 copies of sialoglycoprotein delta (synonym glycophorin B) per normal human erythrocyte. Erythrocytes expressing the product of only one alpha gene contain about 300 000 copies of alpha/cell ...
G. Mallinson+4 more
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Appearance of sialoglycoproteins in encysting cells of Entamoeba histolytica [PDF]
Amoeba-bacterium cultures of Entamoeba histolytica transferred to a hypoosmotic medium depleted of nutrients changed morphologically and biochemically. The cells ejected grains of rice starch, rounded up, and formed a distinct cell wall that was resistant to detergent, bound the sialic acid-specific lectin from Limulus polyphemus, and became ...
Boaz Avron+3 more
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B cells in SLE. Different biological drugs for different pathogenic mechanisms [PDF]
Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disease characterized by a complex multi-factorial pathogenesis and a great clinical polymorphism. SLE is considered to be a B cell disease in which autoantibodies are the major players. Recently,
Carsetti, Rita+3 more
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Isolation and Characteristics of Human Urinary Sialoglycoproteins [PDF]
Three sialoglycoproteins (S1, S2, and S3) have been isolated from normal human urine by ultrafiltration, zone electrophoresis, gel chromatography, and ion-exchange chromatography. The average yields per litre of urine were 0.39 mg (S1), 0.40 mg (S2), and 1.9 mg (S3).
Arne Lundblad+3 more
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CD43 (leukosialin) is a large sialoglycoprotein abundantly expressed on the surface of most cells from the hematopoietic lineage. CD43 is directly involved in the contact between cells participating in a series of events such as signaling, adherence and ...
Frederico Alisson-Silva+8 more
doaj +1 more source
GENES ASSISTED SELECTION AS INSTRUMENT OF THE BIODIVERSITY AND POOLING THE GENETIC DISEASES
The objective it was analysis the prion protein for scrapie resistance genotyping as codon- amino acid at codon 136, 154, 171 from 5 known haplotypes resulting PrP Genotype.
IUDITH IPATE+10 more
doaj
Multifaceted role of sialylation in prion diseases
Mammalian prion or PrPSc is a proteinaceous infectious agent that consists of a misfolded, self-replicating state of a sialoglycoprotein called the prion protein or PrPC. Sialylation of the prion protein N-linked glycans was discovered more than 30 years
Ilia V Baskakov+3 more
doaj +1 more source
Carbohydrate receptor-mediated gene transfer to human T leukaemic cells [PDF]
The mucin-type carbohydrate Tn cryptantigen (GalNAcα1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins,
Berger, Eric G.+8 more
core +2 more sources
Targeting CD22 for the Treatment of B-Cell Malignancies
Nikesh N Shah,1 Lubomir Sokol2 1Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL, USA; 2Department of Malignant Hematology, H.
Shah NN, Sokol L
doaj
Insights into neutralization of animal viruses gained from study of influenza virus [PDF]
It has long been known that the binding of antibodies to viruses can result in a loss of infectivity, or neutralization, but little is understood of the mechanism or mechanisms of this process.
Colonno+17 more
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