Results 51 to 60 of about 5,594 (243)

Plasmodium reichenowi EBA-140 merozoite ligand binds to glycophorin D on chimpanzee red blood cells, shedding new light on origins of Plasmodium falciparum

Parasites & Vectors, 2017
Background All symptoms of malaria are caused by the intraerythrocytic proliferation of Plasmodium merozoites. Merozoites invade erythrocytes using multiple binding ligands that recognise specific surface receptors.
Agata Zerka, Radoslaw Kaczmarek, Marcin Czerwinski, Ewa Jaskiewicz   +3 more
doaj   +1 more source

Overcoming the Blood–Brain Barrier: Multifunctional Nanomaterial‐Based Strategies for Targeted Drug Delivery in Neurological Disorders

Small Science, Volume 4, Issue 12, December 2024.
This review explores the diverse range of nanomaterials, including polymer, lipid, gold, magnetic, and carbon‐based nanostructures, capable of effectively passing the blood–brain barrier (BBB). Moreover, the structure and function of the BBB in both healthy and diseased states are discussed and the potential of nanotechnology in bypassing the BBB to ...
Callan D. McLoughlin, Sarah Nevins, Joshua B. Stein, Mehrdad Khakbiz, Ki‐Bum Lee   +4 more
wiley   +1 more source

Tamm-Horsfall Glycoprotein Enhances PMN Phagocytosis by Binding to Cell Surface-Expressed Lactoferrin and Cathepsin G That Activates MAP Kinase Pathway

Molecules, 2011
The molecular basis of polymorphonuclear neutrophil (PMN) phagocytosis-enhancing activity (PEA) by human purified urinary Tamm-Horsfall glyco- protein (THP) has not been elucidated.
Chia-Li Yu, Chang-Youh Tsai, Ming-Chi Lu, Cheng-Han Wu, Syue-Cian Siao, Song-Chou Hsieh, Ko-Jen Li   +6 more
doaj   +1 more source

Sialoglycoproteins of ejaculated human spermatozoa and seminal plasma [PDF]

International Journal of Andrology, 1984
Ejaculated human sperm were found to possess three major sialoglycoproteins with molecular weights of 30 000, 14 000 and 12 000 and one minor species of 18 000. Liquefied seminal plasma from normal donors contain two major sialoglycoproteins with molecular weights of 17 000 and 15 000 and two minor species of 70 000 and 54 000.
M. Chulavatnatol, C. Wongkome
openaire   +3 more sources

Nonimmunological alterations of glomerular filtration by s-PAF in the rat kidney [PDF]

, 1988
Nonimmunological alterations of glomerular filtration by s-PAF in the rat kidney. Rat kidneys were isolated and perfused with a cell-free perfusion buffer containing 4% albumin.
Camussi, Giovanni, Dennis, Vincent W., Schwertschlag, Ullrich S., Tucker, J. Allan   +3 more
core   +1 more source

Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling

Clinical &Translational Immunology, Volume 13, Issue 9, September 2024.
In this study, we found high Siglec‐7 and Siglec‐9 (ligand) expression in triple negative breast cancer, and to a lower extent in oestrogen receptor positive breast cancer. Moreover, signalling experiments demonstrated that Siglec‐7 signalling is induced by triple negative breast cancer cell lines.
Eline JH van Houtum, Anne HC Valk, Daniel Granado, Jasper Lok, Lune van den Bogaard, Naomi Remkes, Jesper van Eck van der Sluijs, Paul N Span, Lenneke AM Cornelissen, Gosse J Adema   +9 more
wiley   +1 more source

The genetics of cardiovascular disease [PDF]

, 2008
Recent advances in genotyping technology and insights into disease mechanisms have increased interest in the genetics of cardiovascular disease. Several candidate genes involved in cardiovascular diseases were identified from studies using animal models,
Abu-Amero, Aitman, Anna F. Dominiczak, Benhamou, Bhatnagar, Bowcock, Caulfield, Chen, Christian Delles, Clark, Conrad, Cowley, Cupples, Delles, Delles, Delles, Dominiczak, Dominiczak, Dutil, Edwards, Emilsson, Garrett, Good, Graham, Grunfeld, Gunderson, Guzik, Hamilton, Hamilton, Harrap, Hunt, Iwai, Jakubowska, Jeffs, Jeffs, Ji, Kathiresan, Kerr, Klein, Latronico, Levy, Martin W. McBride, Matarín, Matarín, Matsuzaki, McBride, McBride, McCarthy, Monti, Moreno, Mueller, Newhouse, Oniki, Padmanabhan, Padmanabhan, Petretto, Pollex, Rapp, Roodi, Samani, Sandhu, Sandosh Padmanabhan, Sayed-Tabatabaei, Sharma, Staessen, Teo, Tobin, Tobin, Turner, Wallace, Wilson, Zalba, Zimmerli   +72 more
core   +1 more source

CNS/PNS proteoglycans functionalize neuronal and astrocyte niche microenvironments optimizing cellular activity by preserving membrane polarization dynamics, ionic microenvironments, ion fluxes, neuronal activation, and network neurotransductive capacity

Journal of Neuroscience Research, Volume 102, Issue 7, July 2024.
Proteoglycans are important multifunctional components of the central and peripheral nervous systems and represent a diverse group of specialized proteins that stabilize and functionalize these tissues. Abstract Central and peripheral nervous system (CNS/PNS) proteoglycans (PGs) have diverse functional roles, this study examined how these control ...
James Melrose
wiley   +1 more source

Expression of the neural cell adhesion NCAM in endocrine cells of the ovary [PDF]

, 1991
In the adult mammalian ovary morphogenesis and differentiation processes are under hormonal control and, thus, occur in a highly regulated way during the sexual cycle.
Gratzl, Manfred, Lahr, G., Mayerhofer, Artur   +2 more
core   +1 more source

OMIP‐102: 50‐color phenotyping of the human immune system with in‐depth assessment of T cells and dendritic cells

Cytometry Part A, Volume 105, Issue 6, Page 430-436, June 2024.
Abstract We report the development of an optimized 50‐color spectral flow cytometry panel designed for the in‐depth analysis of the immune system in human blood and tissues, with the goal of maximizing the amount of information that can be collected using currently available flow cytometry platforms.
Andrew J. Konecny, Peter L. Mage, Aaron J. Tyznik, Martin Prlic, Florian Mair   +4 more
wiley   +1 more source