Results 11 to 20 of about 4,367 (168)
Essential functions, syntheses and detection of sialyl Lewis X on glycoproteins [PDF]
Exploration of Drug Science, 2023 It is widely acknowledged that sialyl Lewis X (sLeX), the composition and linkage of which are N-acetylneuraminic acid (Neu5Ac) α2-3 galactose (Gal) β1-4 [fucose (Fuc) α1-3] N-acetylglucosamine, is usually attached to the cell surface.
Qiushi Chen, Han Liu, Xuechen Li
doaj +1 more source
In vitro Evaluation of Sialyl Lewis X Relationship with Head and Neck Cancer Stem Cells [PDF]
Otolaryngology - Head and Neck Surgery, 2013 Vincenzo Desiderio +2 more
exaly +2 more sources
Frontiers in Cellular and Infection Microbiology, 2022 Streptococcus oralis is an oral commensal and opportunistic pathogen that can enter the bloodstream and cause bacteremia and infective endocarditis. Here, we investigated the mechanisms of S.
Gurdeep Chahal +8 more
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
alpha2,3-sialyltransferase ST3Gal III modulates pancreatic cancer cell motility and adhesion in vitro and enhances its metastatic potential in vivo. [PDF]
PLoS ONE, 2010 BACKGROUND: Cell surface sialylation is emerging as an important feature of cancer cell metastasis. Sialyltransferase expression has been reported to be altered in tumours and may account for the formation of sialylated tumour antigens.
Marta Pérez-Garay +6 more
doaj +1 more source
Glycan motif profiling reveals plasma sialyl-lewis x elevations in pancreatic cancers that are negative for sialyl-lewis A. [PDF]
Mol Cell Proteomics, 2015 The sialyl-Lewis A (sLeA) glycan forms the basis of the CA19-9 assay and is the current best biomarker for pancreatic cancer, but because it is not elevated in ∼25% of pancreatic cancers, it is not useful for early diagnosis. We hypothesized that sLeA-low tumors secrete glycans that are related to sLeA but not detectable by CA19-9 antibodies. We used a
Tang H +12 more
europepmc +3 more sources
Chronic kidney disease linked to SARS-CoV-2 infection: a case report
BMC Nephrology, 2021 Background The recent COVID-19 pandemic has raised concerns about patient diagnosis and follow-up of chronically ill patients. Patients suffering from chronic illnesses, concomitantly infected by SARS-CoV-2, globally tend to have a worse prognosis and ...
Georges Tarris +10 more
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Frontiers in Immunology, 2022 BackgroundCarbohydrate Lewis antigens including sialyl Lewis A (sLeA), sialyl Lewis X (sLeX), Lewis X (LeX), and Lewis Y (LeY) are the commonest cell surface glycoconjugates that play pivotal roles in multiple biological processes, including cell ...
Zhi Ma +7 more
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Evidence for a lectin specific for sulfated glycans in the salivary gland of the malaria vector, Anopheles gambiae. [PDF]
PLoS ONE, 2014 Salivary gland homogenate (SGH) from the female mosquitoes Anopheles gambiae, An. stephensi, An. freeborni, An. dirus and An. albimanus were found to exhibit hemagglutinating (lectin) activity. Lectin activity was not found for male An.
Ivo M B Francischetti +3 more
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Staining of E-selectin ligands on paraffin-embedded sections of tumor tissue
BMC Cancer, 2018 Background The E-selectin ligands expressed by cancer cells mediate adhesion of circulating cancer cells to endothelial cells, as well as within tissue microenvironments important for tumor progression and metastasis.
Mylène A. Carrascal +9 more
doaj +1 more source