Results 31 to 40 of about 4,367 (168)
Characterization of bovine
BMC Genetics, 2012 Background The Sialyl-Lewis X (Slex) is a well-known glycan structure involved in leukocyte homing and recruitment to inflammatory sites. SLex is well conserved among species and is mainly synthesized by FucT-VII in vertebrates.
Laporte Benoît +6 more
doaj +1 more source
Cell Transplantation, 2020 Adult-derived human liver stem/progenitor cells (ADHLSCs) are a promising alternative to orthotopic liver transplantation in the treatment of inborn errors of metabolism.
Pierre Edouard Dollet +9 more
doaj +1 more source
Cellular and Molecular Gastroenterology and Hepatology, 2016 Background & Aims: The cancer antigen 19-9 (CA19-9) is the current best biomarker for pancreatic cancer, but it is not increased in approximately 25% of pancreatic cancer patients at a cut-off value that provides a 25% false-positive rate.
Huiyuan Tang +8 more
doaj +1 more source
A Structural-Reporter Group to Determine the Core Conformation of Sialyl Lewisx Mimetics
Molecules, 2023 The d-GlcNAc moiety in sialyl Lewisx (sLex, 1) acts predominantly as a linker to position the d-Gal and the l-Fuc moieties in the bioactive spatial orientation.
Beatrice Wagner +8 more
doaj +1 more source
One-pot multienzyme synthesis of Lewis x and sialyl Lewis x antigens. [PDF]
Curr Protoc Chem Biol, 2012 AbstractL‐Fucose has been found abundantly in human milk oligosaccharides, bacterial lipopolysaccharides, glycolipids, and many N‐ and O‐linked glycans produced by mammalian cells. Fucose‐containing carbohydrates have important biological functions. Alterations in the expression of fucosylated oligosaccharides have been observed in several pathological
Yu H, Lau K, Li Y, Sugiarto G, Chen X.
europepmc +4 more sources
Human Epidermal Keratinocyte Expression of Sialyl-Lewis X
Journal of Investigative Dermatology, 1992 Cell-surface oligosaccharides can function as ligands for intercellular adhesion receptors, matrix proteins, and growth factors. We report that human neonatal and adult epidermal keratinocytes (KC) express sialyl Lewis X [s-Le(x); SA alpha 2-3Gal beta 1-4(Fuc alpha 1-3)GlcNAc beta 1-3R], a ligand for endothelial and platelet selectins. Freshly isolated
Symington, Frank W +2 more
openaire +2 more sources
Food Frontiers, Volume 7, Issue 4, July 2026.Apple pomace pectin is explored as a sustainable and multifunctional biomaterial for gastric ulcer management. Its unique structural features confer mucoadhesive, anti‐inflammatory, antioxidant, and anti‐Helicobacter pylori activities while enabling nano/microencapsulation of therapeutic agents.
Akash Dhiman +6 more
wiley +1 more source
Sialylated Lewis x Antigen Bearing Glycoproteins in Human Plasma [PDF]
Journal of Proteome Research, 2010 Recent studies have shown that antibodies targeting Lewis x (Le(x)) antigen are a valuable tool in the isolation and identification of glycoproteins in plasma. A focus of this study was to determine whether sialylated Lewis x (sLe(x)) antigen carrying glycoproteins occur in human plasma and whether an antibody targeting this antigen could be used to ...
Wonryeon, Cho +2 more
openaire +2 more sources
BMC Cancer, 2022 Background Routine measurement of tumor markers is not recommended in daily clinical practice for patients with cancer of unknown primary (CUP). We evaluated the diagnostic value of tumor markers in identifying favorable or unfavorable subsets in ...
Shigemasa Takamizawa +14 more
doaj +1 more source
Chemoenzymatic synthesis of the sialyl Lewis X glycan and its derivatives. [PDF]
Carbohydr Res, 2010 A combination of recombinant FKP and alpha-(1-->3)-fucosyltransferase allows the facile synthesis of the sialyl Lewis X tetrasaccharide glycan and its derivatives in excellent yield. In this system, the universal fucosyl donor, guanidine 5'-diphosphate-beta-L-fucose (GDP-fucose), or its analogues can be generated in situ by cofactor recycling using ...
Soriano del Amo D +7 more
europepmc +4 more sources