Results 101 to 110 of about 4,991,463 (296)
Growth and Pubertal Development in Children With Sickle Cell Anaemia at Muhimbili National Hospital 2010 [PDF]
Sickle cell anaemia (SCA) is a genetic disorder with multisystem manifestations. Paediatricians and general practitioners dealing with these patients need to know the overview of the genetics, diagnosis, clinical manifestations, and treatment of sickle ...
Jacob, Theopista
core
Mission: To improve quality of life, life expectancy, and health among people living with sickle cell disease (SCD)
core +1 more source
The Impact of Common Medications on Male Fertility: An Updated Systematic Review
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli +7 more
wiley +1 more source
Managing Chronic Pain if You Have Sickle Cell Disease [PDF]
If you have sickle cell disease (SCD), you may experience chronic pain, which is pain that lasts most days for 6 months or more. Pain management looks different for everyone.
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P-021: THE LIVING WELL WITH SICKLE CELL MOBILE APPLICATION
MATTHEWS A., MATTHEWS M.
doaj +1 more source
Splenectomy is a safe and effective treatment option in selected patients with haematological disease, despite declining referrals over the last 27 years in the era of targeted therapies. Outcomes are favourable when performed laparoscopically and long‐term follow‐up demonstrates sustained haematologic benefit in surviving patients.
Salil Dutt Barrett +9 more
wiley +1 more source
Sickle Cell Amenia in association with α-thalassemia-2 : biosynthetic and hematological studies [PDF]
Patients with Sickle Cell Anemia (SS) associated with homozygous α-thalassemia-2 (-α/-α; βs/βs) are difficult to detect because the in vitro synthesis of hemoglobin chains may be balanced after prolonged incubation (>120 min).
Huisman, Titus Hendrik Jan +2 more
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Gene therapy is revolutionizing treatment paradigms for haemoglobinopathies, establishing a translational framework for disorders that impact red blood cell development. In their paper, Joshi et al. describe the preclinical and early clinical landscape of gene therapies for non‐haemoglobinopathy erythroid disorders and highlight common thematic ...
Gaurav Joshi +3 more
wiley +1 more source
Predict less, prevent more: A familiar mantra for sickle cell anaemia?
Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley +1 more source
Summary Cerebral macrovasculopathy (CV) is a major complication in children with sickle cell anaemia (SCA) and usually requires a long‐term transfusion programme (TP) to prevent stroke. This study aimed to identify factors predicting reversal of CV on TP in a single‐centre newborn cohort. Among 375 patients, 50 presented CV and received TP.
Julie Sommet +16 more
wiley +1 more source

