Results 91 to 100 of about 4,991,463 (296)

Maternal and perinatal outcomes associated with prophylactic erythrocytapheresis in pregnant women with sickle cell disease

International Journal of Gynecology &Obstetrics, EarlyView.
Pedro Junqueira Fleury Silva, Giovanna Santos Pinto Coelho, Luana de Jesus Pires, Camila Olivares Figueira, José Paulo de Siqueira Guida, Fernanda G. Surita, Juliana da‐Costa‐Santos, Bruno Deltreggia Benites, Paula de Melo Campos, Simone Cristina Olenscki Gilli, Sara T. O. Saad, Fernando F. Costa, Maria Laura Costa   +12 more
wiley   +1 more source

In Utero HSC Transplantation for Sickle Cell Disease: A Potential Therapeutic Approach That Overcomes Complications of Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide but has limited treatment options, most of which carry significant side effects. At present, the only curative treatment for SCD is allogeneic or gene‐modified autologous hematopoietic stem cell (HSC) transplantation (Tx).
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Hemoglobin E Disorders in South Gujarat – A Study Of 35 Cases

National Journal of Community Medicine, 2012
Background:Among the inherited disorders of blood, hemoglobinopathies and thalassemia constitute a major bulk of non-communicable genetic disease in India.
B M Jha, Bhavna Gamit, Jitendra Patel, Kunal J Prajapati   +3 more
doaj  

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Fonio (Digitaria exilis and Digitaria iburua) in Nigeria: Regional cultivation patterns, landrace diversity, and farmer knowledge for conserving a climate‐resilient indigenous cereal

PLANTS, PEOPLE, PLANET, EarlyView.
Fonio (Digitaria exilis and Digitaria iburua) cereals are valued for their drought resilience, adaptability to poor soils, and cultural importance. In Nigeria, where both species are cultivated, fonio has declined due to labor‐intensive processing, lower yields, and changing livelihood choices. By documenting 21 landraces (15 D. exilis and 6 D. iburua),
Ishaq Muawiyya, Abubakar Bello, George P. Burton, Philippa Ryan, Maria S. Vorontsova   +4 more
wiley   +1 more source

Exploring the Correlation Between Surgical Depth and Postoperative Voice Rest Duration in a Rabbit Phonomicrosurgery Model

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective The optimal duration of voice rest after phonomicrosurgery remains a subject of debate, as clinical studies on its effect on vocal fold wound healing have yielded conflicting results, and a controlled animal model for investigating voice rest is currently unavailable. This study aimed to determine the optimal postoperative voice rest
Lin‐Lin Lan, Qiu‐Rong Yang, Pei‐Yun Zhuang   +2 more
wiley   +1 more source

Variations in mitochondrial genome as potential prognostic markers in sickle cell disease

Haematologica
Alterations in the mitochondrial genome integrity, including changes in mitochondrial DNA copy number (mtDNA-CN) and accumulation of mtDNA mutations, are associated with aging and diverse disorders, often linked to underlying systemic inflammation and ...
Rudra Ray, Haiou Li, Shijinqiu Gao, Nancy Asomaning, Kang Le, Maliha M. Ahmad, Xunde Wang, Yuesheng Li, Sayuri Kamimura, Clifton L. Dalgard, Chengyu Liu, Zenaide M.N. Quezado, Justin Lack, Laxminath Tumburu, Swee Lay Thein   +14 more
doaj   +1 more source

Taxogenomic Characterization and Comparative Genomic Analysis of Hermanozyma buritii sp. nov., f.a., a Yeast Species Isolated From Plants and Soil

Yeast, EarlyView.
Isolation of the novel yeast species Hernanozyma buritii sp. nov. from soil and plant in Brazil, followed by phylogenetic characterization and genome analysis, highlighting its relationship with closely related taxa and genomic features associated with mating, pulcherriminic acid biosynthesis, and iron‐dependent pigmentation.
Vitória Petra de O. Barros, Ana Raquel O. Santos, Júlio Ricardo M. Silva, Paula B. Morais, Thiago M. Batista, Daniela L. Souza, Rosangela Santa‐Brígida, Marlúcia B. Martins, Glória R. Franco, Marc‐André Lachance, Carlos A. Rosa, Melissa Fontes Landell   +11 more
wiley   +1 more source

Comparison of Definitions of Severe Maternal Morbidity: A National Cohort Study Using Administrative Data

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To understand agreement between definitions of severe maternal morbidity (SMM), the reasons for disagreement and the impact the outcome definition may have on the measurement of ethnic and socioeconomic inequalities. Design A national cohort study using administrative data. Setting The English National Health Service.
Ian Henderson, Dorothea Geddes‐Barton, Raph Goldacre, Marian Knight   +3 more
wiley   +1 more source

Comparative Outcomes of Early versus Delayed Penile Prosthesis Insertion in Patients With Ischaemic Priapism—Long‐Term Outcome Experience From a Single High‐volume Centre

Andrology, EarlyView.
ABSTRACT Background and Objectives Ischaemic priapism (IP) is a urological emergency that can lead to erectile dysfunction (ED) if not treated promptly. This study aims to evaluate and compare clinical outcomes between early and delayed penile prosthesis insertion in patients with IP.
King Sum Tong, Karl H. Pang, Jerry T. Y. Lau, David J. Ralph, Asif Muneer, Hussain M. Alnajjar   +5 more
wiley   +1 more source