Results 251 to 260 of about 10,746,438 (360)

Osteomyelitis Complicating Sickle Cell Disease. [PDF]

J Belg Soc Radiol
Özcan F, Vanhoenacker F, Catry F.
europepmc   +1 more source

Gene Therapy in a Patient with Sickle Cell Disease: Brief Report

New England Journal of Medicine, 2017
J. Ribeil, S. Hacein-Bey-Abina, E. Payen, A. Magnani, M. Semeraro, E. Magrin, L. Caccavelli, B. Neven, P. Bourget, W. El Nemer, P. Bartolucci, Leslie Weber, H. Puy, J. Meritet, D. Grevent, Y. Beuzard, S. Chrétien, T. Lefèbvre, R. W. Ross, O. Nègre, G. Veres, L. Sandler, S. Soni, M. de Montalembert, S. Blanche, P. Leboulch, M. Cavazzana   +26 more
semanticscholar   +1 more source

Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells

Advanced Functional Materials, Volume 36, Issue 5, 15 January 2026.
CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham, Jose Gabriel Castro, Lisette C. Werba, Joseph Amitrano, Luke Fardone, Kevin P. Francis, Anand Ramamurthi, Michael J. Layden, Helen O. McCarthy, Tomas Gonzalez‐Fernandez   +9 more
wiley   +1 more source

A pilot study of dronabinol for the treatment of pain in sickle cell disease. [PDF]

Pilot Feasibility Stud
Curtis SA, Jhawar R, Bellis J, McCuskee S, Devine L, Roberts JD.   +5 more
europepmc   +1 more source

Ventricular hypertrophy and restrictive lung profile in young patients with sickle cell disease

, 2014
Osvaldo Alves de Menezes Neto
openalex   +1 more source

Protein S Enhances the Phagocytosis of Phosphatidylserine‐Exposing Erythrocytes: Implications in Sickle Cell Disease

American Journal of Hematology, Volume 101, Issue 1, Page 26-40, January 2026.
ABSTRACT The major anticoagulant Protein S (PROS1) also contributes to the phagocytosis of apoptotic cells by bridging exposed phosphatidylserine (PtdSer) to the MerTK receptor on macrophages (efferocytosis). Whether PROS1 is involved in the splenic clearance of PtdSer‐positive senescent and altered erythrocytes such as erythrocyte ghosts (eryghosts ...
Claire Auditeau, Aurélie Fricot, Raphaël Gauthier, Abdoulaye Sissoko, Zeynep Cacan, Céline Gounou, Laure Joseph, Sandra Manceau, Slimane Allali, Michael Dussiot, Mickael Marin, Alexis Lavergne, Mariem Khamari, Sophie Moog, Elsa Bianchini, Laetitia Claer, Sandrine Laurance, Valentine Brousse, Sébastien Eymieux, Philippe Roingeard, Pascal Amireault, Thiago Trovati Maciel, Alain Brisson, Pierre Buffet, François Saller, Delphine Borgel, Camille Roussel   +26 more
wiley   +1 more source

Biomarker signatures for sickle cell pain. [PDF]

Blood Adv
Gupta K, Kumaresan V.
europepmc   +1 more source

Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th‐Century Ontario

American Journal of Human Biology, Volume 38, Issue 1, January 2026.
ABSTRACT Objectives This study examines how settler‐driven environmental change shaped malaria transmission and mortality in 19th‐century southern Ontario. It aimed to understand the biosocial and ecological conditions that sustained endemic malaria in a temperate, colonial context.
Amanda Cooke, Megan B. Brickley
wiley   +1 more source

Pulmonary Hypertension Associated With Sickle Cell Disease and Schistosomiasis. [PDF]

Pulm Circ
Mickael C, Kabwe JC, Fonseca Balladares D, Bai AS, Nolan K, Lee MH, Kumar R, Hilton JF, Phiri J, Musonda T, Tuscan K, Sanders L, Stenmark KR, Buehler PW, Sinkala E, Irwin DC, Mazimba S, Graham BB.   +17 more
europepmc   +1 more source

Unveiling the Genetic Association Between Hemoglobin Concentration and Amyotrophic Lateral Sclerosis

Brain and Behavior, Volume 16, Issue 1, January 2026.
This study identified a causal relationship between genetically predicted hemoglobin (Hb) concentration and amyotrophic lateral sclerosis (ALS) through Mendelian randomization (MR), and integrated RNA‐seq and RT‐qPCR analyses to highlight BACH1, FLVCR1, and TRIM58 as potential genes involved in this association.
Hongmei Luo, Yujie Yang, Xiaojian Cao, Chunchu Deng, Hong Chen   +4 more
wiley   +1 more source