Results 261 to 270 of about 10,746,438 (360)

Newborn screening for sickle cell disease in Caluquembe, southwestern Angola, 2024-2025. [PDF]

PLoS One
Su JJ, Kupua VS, Cummings D, Jacobsen KH.   +3 more
europepmc   +1 more source

Anti‐Inflammatory, Antioxidant, Molecular Docking and Pharmacokinetics Properties of Cycloeucalenone Isolated From Musa × paradisiaca L. Fruit Peels

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
ABSTRACT This study isolated a compound with anti‐inflammatory properties from Musa × paradisiaca fruit peels. The methanol extract was partitioned, and the hexane fraction with the best bioactivity was subjected to column chromatography before characterization via Fourier transform infrared (FTIR), UV–visible (UV–VIS) and NMR analysis.
Ibeabuchi J. Ali, Kolawole A. Olofinsan, Goodnews O. Ikeh, Ndidiamaka H. Okorie, Cyril C. Adonu, Romanus C. Omeh, Blessing C. Idoko, Pamela E. Nnamani   +7 more
wiley   +1 more source

Acoustic probing of new biomarkers for rapid sickle cell disease screening.

Lab Chip
Sridhar N, Song M, Stowell MHB, Hassell KL, Ding X.   +4 more
europepmc   +1 more source

Association between sickle cell anaemia and dental caries among children in Nigeria. [PDF]

BMC Oral Health
Afolabi JB, Oziegbe EO, Adegoke SA, Adefehinti O, Oyetola EO, Foláyan MO.   +5 more
europepmc   +1 more source

Human Protein Z as the Second Known Heme‐Binding Protein from the Endogenous Blood Coagulation Inhibitor System

ChemBioChem, Volume 27, Issue 1, January 2026.
Protein Z is a vitamin K‐dependent anticoagulant with elusive molecular functions. Herein, it is shown that heme binds to protein Z and induces conformational changes. One histidine‐based heme‐binding motif is identified. High heme‐binding affinity and functional effects are demonstrated on protein level. These findings shed new light on the structural
Paula Lindemann, Marie‐T. Hopp
wiley   +1 more source

Burden of sickle cell anemia in Africa: A systematic review and meta-analysis. [PDF]

PLoS One
Jonani B, Kasule EC, Herman BR, Arturo JF, Mugambwa MC, Stephen S, Mundaka JB, Kwizera R, Mboowa G, Bongomin F.   +9 more
europepmc   +1 more source

Negative Pressure Wound Therapy in an Immunocompromised Child: A Case Report From a Resource‐Limited Setting in Ghana

Clinical Case Reports, Volume 14, Issue 1, January 2026.
ABSTRACT An 8‐year‐old immunocompromised girl with a large septic wound on the left thigh was admitted to the facility after the failure of home treatment by the family. The child was generally stable aside from the difficulty in walking on the left leg.
Matilda Mawusi Kodjo, Kennedy Kofi Kru, Belinda Dziedzorm Korley, Cynthia Tetteh, Wise Awunyo, Agani Afaya   +5 more
wiley   +1 more source

Safety, Pharmacokinetics, and Pharmacodynamics of Osivelotor for Sickle Cell Disease: First‐in‐Human Studies in Healthy Participants and Patients

Clinical Pharmacology &Therapeutics, Volume 119, Issue 1, Page 120-130, January 2026.
The investigational agent osivelotor, a small molecule hemoglobin (Hb) modifier in development for the treatment of sickle cell disease (SCD), acts by increasing Hb‐oxygen affinity and inhibiting the polymerization of sickle Hb. We report safety, pharmacokinetic (PK), and pharmacodynamic (PD) data from the first two phase 1 clinical trials of ...
Eleanor A. Lisbon, R. Clark Brown, Andrew Redfern, Ken Duchin, Aline Barth, Erika S. Roberts, Polo Gaputan, Kobina Dufu, Arthur Lo, Mira Patel Pochron, David R. Archer, Wai Chin, Karena Kong, Carla B. Washington, Adeyemi Adenola, Eric I. Zimmerman   +15 more
wiley   +1 more source

Building a Comprehensive Sickle Cell Disease Program in Western Kenya: A Decade of Experience and Growth. [PDF]

Ann Glob Health
Njuguna F, Kilach C, Njuguna C, Ayaye E, Wanjiku C, Korir R, Bor C, Midiwo N, Aliwa E, Oburah E, Mbunya S, Kipkoech J, Etling MA, Severance T, Nessle CN, Vik T, Kumar M, Roberson C, Greist A.   +18 more
europepmc   +1 more source

ASSESSMENT OF CYTO-MORPHOLOGICAL CHANGES IN EPITHELIAL ORAL MUCOSA AMONG SICKLE CELL ANEMIA PATIENTS ATTENDING MANAGIL PEDIATRIC TEACHING HOSPITAL, GEZIRA STATE ,SUDAN (2017).

, 2019
Safa Mustafa I. Elsadig, Abdelraheem A. babeker, Wed elbahar H.Aballah.   +2 more
openalex   +2 more sources