Results 51 to 60 of about 105,245 (307)

Búsqueda de hemoglobinas anormales en los recién nacidos en las grandes alturas.

Revista Médica Herediana, 1997
Se hizo un muestreo para detectar hemoglobinas anormales en Recién Nacidos (RN) de tres ciudades andinas situadas en el Perú: Cerro de Pasco, Huancayo y Puno. Estas ciudades estan situadas en altitudes que fluctúan entre los 3,500 a 4,400 m.
Dante ROA, María del Pilar AGUINAGA, Wilson RUIZ, Víctor ULLOA, Ernest TURNER   +4 more
doaj  

Epidemiological and comorbidity burden in transfusion-dependent patients with thalassemia and sickle cell disease in Greece

Annals of Hematology
TDT and SCD are hereditary hemoglobinopathies that require lifelong red blood cell transfusions. Modern treatment has increased survival, exposing patients to transfusion-related problems such iron excess.
Sophia Delicou, Aikaterini Xydaki, Vassiliki Kamposou, Sabrina Goga, Anthimos Papadopoulos, Christina Rina, Maria Moraki   +6 more
doaj   +1 more source

Sickle Cell Data Collection Program Brief : Hospital Encounters Among Adults Living With Sickle Cell Disease in Georgia 2012-2016 [PDF]

The Georgia Sickle Cell Data Collection Program (SCDC) identified 5,405 adults living with sickle cell disease in Georgia from 2012 through 2016. Adults with sickle cell disease live in almost every county throughout Georgia.Nearly nine in 10 (88%) of ...

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ANK1 and EPB41 Variants and the Risk of Steroid‐Induced Osteonecrosis

Arthritis &Rheumatology, EarlyView.
Objective Steroid‐induced osteonecrosis of the femoral head (SONFH) is a refractory skeletal disorder influenced by genetic and environmental factors. However, conclusive pathogenic genetic evidence remains elusive due to the limited exploration of rare damaging variants. In this study, we aimed to identify rare variants associated with SONFH.
Shengbao Chen, Xianmin Zhu, Zhongzhong Chen, Wei Chen, Hussam Alkaissi, Zeng Zhang, Yun Gao, Junhui Yin, Xiangtian Yu, Qiong Fu, Youshui Gao, Zhenzhong Zhu, Qianying Cai, Pengwei Zhang, Weibin Chen, Xin Zhao, Xiaojin Wu, Karel Pacak, Dongxu Jin, Chunde Bao, Zhengping Zhuang, Changqing Zhang   +21 more
wiley   +1 more source

What you should know about sickle cell trait [PDF]

Sickle cell trait (SCT) is not a mild form of sickle cell disease. Having SCT simply means that a person carries a single gene for sickle cell disease (SCD) and can pass this gene along to their children.

core   +2 more sources

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

Relationships Between Markers of Iron Status and Hematological Parameters in Patients With Sickle Cell Disease

Advances in Hematology
Based on the relationship between the intracellular concentration of sickle hemoglobin S (HbS) and the delay that occurs prior to the onset of sickling following deoxygenation, targeting the intracellular HbS concentration is a recognized therapeutic ...
Nermi L. Parrow, Jason M. Doherty, Anna Conrey, Swee Lay Thein, Robert E. Fleming   +4 more
doaj   +1 more source

Sickle Cell Disease (SCD) in California, 2016 [PDF]

We found 4,689 people with SCD were living in California in 2016.CS 310397-C2016-snapshot-sickle-cell-ca-508.pdf?deliveryName=USCDC_1391 ...

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Evaluating the (comparative) safety profile of the novel oral polio vaccine type 2 using individual case safety reports in VigiBase

British Journal of Clinical Pharmacology, EarlyView.
Aim Novel oral polio vaccine type 2 (nOPV2) was used under the WHO emergency use listing for circulating vaccine‐derived polio virus (cVDPV) outbreaks from 2021 to 2023. We assessed nOPV2 adverse events following immunization (AEFIs) and compared its safety profile to other vaccines using VigiBase.
Comfort Kunak Ogar, Malede Mequanent Sisay, Leonardo Roque‐Pereira, Christine Leopold, Patrick C. Souverein, Aukje K. Mantel‐Teeuwisse, Marie L. De Bruin   +6 more
wiley   +1 more source

Antiviral response and HIV-1 inhibition in sickle cell disease

iScience
Summary: Sickle cell disease (SCD) is characterized by hemolysis, vaso-occlusion, and ischemia. HIV-1 infection was previously shown to be suppressed in SCD PBMCs.
Namita Kumari, Asrar Ahmad, Clemilson Berto-Junior, Andrey Ivanov, Fayuan Wen, Xionghao Lin, Sharmin Diaz, Iheanyi Okpala, James G. Taylor, VI, Marina Jerebtsova, Sergei Nekhai   +10 more
doaj   +1 more source