Results 61 to 70 of about 4,991,463 (296)

Epidemiological and comorbidity burden in transfusion-dependent patients with thalassemia and sickle cell disease in Greece

Annals of Hematology
TDT and SCD are hereditary hemoglobinopathies that require lifelong red blood cell transfusions. Modern treatment has increased survival, exposing patients to transfusion-related problems such iron excess.
Sophia Delicou, Aikaterini Xydaki, Vassiliki Kamposou, Sabrina Goga, Anthimos Papadopoulos, Christina Rina, Maria Moraki   +6 more
doaj   +1 more source

Model‐Informed Evaluation of Hydroxyurea Exposure During Lactation

Clinical Pharmacology &Therapeutics, EarlyView.
Hydroxyurea is a cornerstone therapy for sickle cell anemia; however, evidence guiding its use during lactation remains limited. This study aimed to develop a population pharmacokinetic (PK) model to characterize hydroxyurea disposition in maternal plasma and breast milk, and to quantify infant exposure under clinically relevant breastfeeding scenarios.
Anhar Hosawi, Kei Irie, Min Dong, Julie Ware, Russell Ware, Tomoyuki Mizuno   +5 more
wiley   +1 more source

Association between maternal pre‐pregnancy body mass index and maternal and neonatal outcomes in Saudi Arabia: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective The body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) of the mother before pregnancy and the growth of weight during pregnancy are both important perinatal health determinants. The aim of the present study was to examine the association between the maternal BMI and obstetric and ...
Randa Elsayed, Eman Al Ali, Rawabi AlAbdulgader, Shouq ALshuwayfie, Hasna Almutawa, Zahra Alhawaj, Bayan Albesher, Fatimah Almuaybid   +7 more
wiley   +1 more source

Sickle Cell Disease (SCD) in California, 2016 [PDF]

We found 4,689 people with SCD were living in California in 2016.CS 310397-C2016-snapshot-sickle-cell-ca-508.pdf?deliveryName=USCDC_1391 ...

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Relationships Between Markers of Iron Status and Hematological Parameters in Patients With Sickle Cell Disease

Advances in Hematology
Based on the relationship between the intracellular concentration of sickle hemoglobin S (HbS) and the delay that occurs prior to the onset of sickling following deoxygenation, targeting the intracellular HbS concentration is a recognized therapeutic ...
Nermi L. Parrow, Jason M. Doherty, Anna Conrey, Swee Lay Thein, Robert E. Fleming   +4 more
doaj   +1 more source

Fetal growth trajectories and neonatal outcomes: A French population‐based study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study assesses whether fetal growth trajectories are associated with neonatal outcomes. Methods The study population included 8537 singleton liveborn infants from the 2021 French National Perinatal Survey. Fetal growth trajectories were assessed between second and third trimester routine ultrasounds and between the third ...
Pierre Gibert, Alice Hocquette, Camille Le Ray, Jennifer Zeitlin, Isabelle Monier, Anne Ego, ENP2021 Study Group, Camille Le Ray, Nathalie Lelong, Hélène Cinelli, Béatrice Blondel, Nolwenn Regnault, Virginie Demiguel, Elodie Lebreton, Benoit Salanave, Jeanne Fresson, Annick Vilain, Thomas Deroyon, Philippe Raynaud, Sylvie Rey, Khadoudja Chemlal, Nathalie Rabier‐Thoreau, Frédérique Collombet‐Migeon   +22 more
wiley   +1 more source

Antiviral response and HIV-1 inhibition in sickle cell disease

iScience
Summary: Sickle cell disease (SCD) is characterized by hemolysis, vaso-occlusion, and ischemia. HIV-1 infection was previously shown to be suppressed in SCD PBMCs.
Namita Kumari, Asrar Ahmad, Clemilson Berto-Junior, Andrey Ivanov, Fayuan Wen, Xionghao Lin, Sharmin Diaz, Iheanyi Okpala, James G. Taylor, VI, Marina Jerebtsova, Sergei Nekhai   +10 more
doaj   +1 more source

Anti‐Erythrocyte Antibody Formation in Individuals With and Without Known Sensitisation Pathways Reflecting Indications for Extended Immunohaematology Screening

Journal of Clinical Laboratory Analysis, EarlyView.
– The yearly incidence of anti‐red blood cell antibodies stratified by participant groups and temporal evolution. – Overall significance p = 3.756 × 10−29. ABSTRACT Background Blood transfusion therapies are of vital importance for many patient groups.
Milanka Milosavić, Marko Lilić, Gordana Guzijan, Dušan Vučetić   +3 more
wiley   +1 more source

Get screened to know your sickle cell status [PDF]

To find out whether you or your loved one has sickle cell disease (SCD) or sickle cell trait (SCT), blood tests must be done to screen for these conditions.

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P-058: INFLUENCE OF HEME OXYGENASE-I GENE PROMOTER POLYMORPHISM ON THE VASO OCCLUSIVE CRISIS OF SICKLE CELL ANEMIA PATIENTS OF EASTERN INDIA

HemaSphere, 2022
MEHER S., MOHANTY P., PATEL S., DAS K., SAHOO S., DEHURY S., DASH B.   +6 more
doaj   +1 more source