Analysis of Coronavirus Envelope Protein with Cellular Automata (CA) Model [PDF]
The reason of significantly higher transmissibility of SARS Covid (2019 CoV-2) compared to SARS Covid (2003 CoV) and MERS Covid (2012 MERS) can be attributed to mutations reported in structural proteins, and the role played by non-structural proteins (nsps) and accessory proteins (ORFs) for viral replication, assembly, and shedding.
arxiv
A deep convolutional neural network for classification of red blood cells in sickle cell anemia
Sickle cell disease (SCD) is a hematological disorder leading to blood vessel occlusion accompanied by painful episodes and even death. Red blood cells (RBCs) of SCD patients have diverse shapes that reveal important biomechanical and bio-rheological ...
Mengjia Xu+5 more
semanticscholar +1 more source
Hematological and hemorheological determinants of the six-minute walk test performance in children with sickle cell anemia. [PDF]
The six-minute walk test is a well-established submaximal exercise reflecting the functional status and the clinical severity of sickle cell patients. The aim of the present cross-sectional study was to investigate the biological determinants of the six ...
Xavier Waltz+14 more
doaj +1 more source
Using Biological Variables and Social Determinants to Predict Malaria and Anemia among Children in Senegal [PDF]
Integrating machine learning techniques in healthcare becomes very common nowadays, and it contributes positively to improving clinical care and health decisions planning. Anemia and malaria are two life-threatening diseases in Africa that affect the red blood cells and reduce hemoglobin production.
arxiv
Lack of mortality in 22 children with sickle cell anemia and severe malarial anemia [PDF]
Retrospective studies suggest that there is high mortality in children with sickle cell anemia (SCA) and severe malaria. We assessed mortality in Ugandan children with severe malarial anemia (SMA, n = 232) or cerebral malaria (CM, n = 267) by sickle cell
Bangirana, Paul+5 more
core +1 more source
Association between diffuse myocardial fibrosis and diastolic dysfunction in sickle cell anemia.
Sickle cell anemia (SCA)-related cardiomyopathy is characterized by diastolic dysfunction and hyperdynamic features. Diastolic dysfunction portends early mortality in SCA.
O. Niss+8 more
semanticscholar +1 more source
Haptoglobin gene polymorphisms and interleukin-6 and -8 levels in patients with sickle cell anemia
BACKGROUND: Haptoglobin genotypes, and interleukin-6 and -8 participate in the pathophysiology of sickle cell anemia. The expression of cytokines is regulated by genetic mechanisms however the effect of haptoglobin polymorphisms on these cytokines is not
Bruna Spinella Pierrot-Gallo+5 more
doaj +1 more source
Studies on the Hemoglobin of Cooley's Anemia and Cooley's Trait [PDF]
The diseases sickle cell anemia and Cooley's anemia (also known as thalassemia or Mediterranean anemia) have associated with them "minor" or "trait" forms of the disease in which the symptomatology is minimal, and the abnormalities in the red cells are ...
Rich, Alexander
core
Publisher's Note: There is an [Inside Blood Commentary][1] on this article in this issue. Sickle cell anemia (SCA) carries orphan disease designation in the United States, with ∼2000 affected infants born annually and fewer than 100 000 persons living ...
Patrick T. McGann+2 more
semanticscholar +1 more source
Objective: To evaluate the association between clinical, pulmonary, and cardiovascular findings in patients with sickle cell disease and, secondarily, to compare these findings between sickle cell anemia patients and those with other sickle cell diseases.
Maria Christina Paixão Maioli+5 more
doaj +1 more source