Results 11 to 20 of about 5,240,823 (173)
An immune basis for malaria protection by the sickle cell trait. [PDF]
BACKGROUND: Malaria resistance by the sickle cell trait (genotype HbAS) has served as the prime example of genetic selection for over half a century. Nevertheless, the mechanism of this resistance remains the subject of considerable debate.
Alexander, ND +43 more
core +1 more source
Background: Sickle cell disease contributes substantially to mortality in children younger than 5 years in sub-Saharan Africa. In Uganda, 20 000 babies per year are thought to be born with sickle cell disease, but accurate data are not available.
Grace Ndeezi, MBChB PhD +10 more
doaj +1 more source
Co-Inheritance of Sickle Cell Trait and Thalassemia Mutations in South Central Iran [PDF]
Background: We aimed to determine the incidence of co-inheritance as well as interaction of sickle cell trait (SCT) and αthal/βthal mutations in south and south central of Iran.
N Saleh-gohari, M Mohammadi-Anaie
doaj +1 more source
Prevalence of sickle cell disease and sickle cell trait in national neonatal screening studies
Sickle cell anemia is the best known hereditary blood disorder; there are serious complications associated with the condition. Diagnosis and early intervention reduce morbidity and mortality.
Luciana Garcia Lervolino +5 more
doaj +1 more source
A Unique Cause of Intestinal and Splenic Infarction in a Sickle Cell Trait Patient
Sickle-cell trait is a common genetic abnormality in the African American population. A sickle-cell crisis in a patient with sickle-cell trait is uncommon at best. Abdominal painful crises are typical of patients with sickle cell anemia.
Sofya H. Asfaw +5 more
doaj +1 more source
Background. To report a case of a pregnant woman with sickle cell trait (SCT) who presented with unilateral proliferative sickle cell retinopathy. Case Presentation.
Sepideh Ghods +7 more
doaj +1 more source
Knowledge and Attitudes towards Sickle Cell Disease Screening: A Study of Members of the UK Sickle Cell Society [PDF]
Over the past fifty years there has been an increase in the number of people in the UK who have a Sickle Cell Disorder (SCD) or are carriers. This increase has led to an expansion in research in this area; however one particular area that has not been ...
Millan, Jenny +2 more
core +7 more sources
Sickle cell hemoglobin D disease First reported case in IRAN [PDF]
A case of sickle cell Hb D disease IS reported in young Iranian male. the father of whom carried an AS sickle cell trait and the mother an AD trait. This disease was diagnosed by Hb electrophoresis. agar gel electrophoresis sickling and solubility tests.
mohamad mehdi aflatouni, mohamad malek
doaj +1 more source
Bacteraemia in Kenyan children with sickle-cell anaemia: a retrospective cohort and case-control study. [PDF]
BACKGROUND: In sub-Saharan Africa, more than 90% of children with sickle-cell anaemia die before the diagnosis can be made. The causes of death are poorly documented, but bacterial sepsis is probably important.
Uyoga, Sophie +44 more
core +1 more source
The scope of clinical morbidity in sickle cell trait
Sickle cell trait (SCT), the heterozygous state of the sickle hemoglobin beta globin gene (HbAS) is carried by as many as 100 million individuals including up to 25% of the population in some regions of the World.
Azza A.G. Tantawy
doaj +1 more source

