Results 31 to 40 of about 5,240,823 (173)
Sickle Cell Disease: Historical Overview and Current Therapies
Prenatal Diagnosis, EarlyView.ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde +4 more
wiley +1 more source
BMC Research Notes, 2019 Objective It is estimated that 50% to 90% of infants born with (SCA) in sub-Saharan Africa die before 5 years old. Northern Darfur State at western Sudan region has a multiethnic population with a high frequency of sickle cell anaemia, but little about ...
Mudathir A. Adam +2 more
doaj +1 more source
Sickle cell trait: not as benign as once thought [PDF]
Journal of Community Hospital Internal Medicine Perspectives, 2014 We describe a case of renal papillary necrosis in a middle-aged female with sickle cell trait who presented with gross hematuria. We wish to highlight this case for several reasons. Sickle cell trait is often viewed as a benign condition despite the fact
Uqba Khan +4 more
doaj +1 more source
PLANTS, PEOPLE, PLANET, EarlyView.Fonio (Digitaria exilis and Digitaria iburua) cereals are valued for their drought resilience, adaptability to poor soils, and cultural importance. In Nigeria, where both species are cultivated, fonio has declined due to labor‐intensive processing, lower yields, and changing livelihood choices. By documenting 21 landraces (15 D. exilis and 6 D. iburua),
Ishaq Muawiyya +4 more
wiley +1 more source
Safety of Pegfilgrastim (Neulasta) in Patients with Sickle Cell Trait/Anemia
Case Reports in Hematology, 2013 Pegfilgrastim (Neulasta) is a recombinant filgrastim (human granulocyte colony-stimulating factor (G-CSF)) attached to a polyethylene glycol (PEG) molecule and is given as part of chemotherapy regimens that are associated with significant ...
Pashtoon Murtaza Kasi +2 more
doaj +1 more source
Predict less, prevent more: A familiar mantra for sickle cell anaemia?
British Journal of Haematology, EarlyView.Commentary on: Sommet J, Boizeau P, Haouari Z, et al. Identification of predictive factors for reversal of cerebral vasculopathy in an original longitudinal cohort study in newborns with sickle cell anaemia. Br J Haematol. 2026 (Online ahead of print). doi: 10.1111/bjh.70726.
Charles T. Quinn
wiley +1 more source
What you should know about sickle cell trait [PDF]
Sickle cell trait (SCT) is not a mild form of sickle cell disease. Having SCT simply means that a person carries a single gene for sickle cell disease (SCD) and can pass this gene along to their children.
core +2 more sources
Sickle cell anaemia with and without crises: An observational study of pregnancy outcomes
British Journal of Haematology, EarlyView.Summary We assessed the pregnancy outcomes of patients with sickle cell crises. We carried out a retrospective study of 2 698 556 pregnancies in Quebec, Canada between 1989 and 2022. The primary exposure was sickle cell anaemia with crisis during or outside of pregnancy. Outcomes included severe maternal morbidity and other pregnancy complications.
Nathalie Auger +8 more
wiley +1 more source
The ethnic distribution of sickle cell disease in Sudan
The Pan African Medical Journal, 2014 Sickle cell disease (SCD) is one of the most common inherited disorders of haemoglobin in Africa and it is expected that sickle cell trait varies in frequency in different areas in Sudan.
Majdi Mohammed Sabahelzain, Hanan Hamamy
doaj +1 more source
Journal of Community Hospital Internal Medicine Perspectives, 2021 In this report, we present a 29-year-old African American female who was brought to a local emergency department after being found unresponsive by her mother.
Ava Runge, Danielle Brazel, Zahra Pakbaz
doaj +1 more source