Results 21 to 30 of about 36,963 (195)

Basal and LPS-stimulated inflammatory markers and the course of depression and anxiety symptoms

open access: yesEuropean Psychiatry, 2023
Introduction Multiple studies show an association between inflammation –characterized by increased blood levels of C-reactive protein (CRP) and pro-inflammatory cytokines– and major depressive disorder (MDD).
W. A. Van Eeden
doaj   +1 more source

Workplace Bullying and Medically Certified Sickness Absence: Direction of Associations and the Moderating Role of Leader Behavior

open access: yesFrontiers in Psychology, 2019
The aim of this study was to determine (1) associations between workplace bullying and subsequent risk and duration of medically certified sickness absence, (2) whether employees’ perceptions of supportive, fair, and empowering leader behavior moderate ...
Morten Birkeland Nielsen   +3 more
doaj   +1 more source

Neuro-Inflammatory Response and Brain-Peripheral Crosstalk in Sepsis and Stroke

open access: yesFrontiers in Immunology, 2022
Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and disability. There is renewed attention on peripheral inflammatory signaling as a way of modulating the post-ischemic neuro-inflammatory process.
Lena Bourhy   +7 more
doaj   +1 more source

Cytokine, Sickness Behavior, and Depression [PDF]

open access: yesImmunology and Allergy Clinics of North America, 2006
Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness. Clarifying the way the brain processes information generated by the innate immune system is accompanied by a progressive elucidation of the cellular and molecular components of the intricate system that mediates cytokine ...
openaire   +5 more sources

Sickness behaviour: Causes and effects

open access: yesSouth African Family Practice, 2003
This paper discusses sickness behavior as a central motivational state. It deals with the adaptational value and underlying mechanisms of sickness behavior and with the consequences of the body's failure to terminate the activity of the symptoms ...
M. Viljoen
doaj   +1 more source

Tumor Necrosis Factor (TNF) Is Required for Spatial Learning and Memory in Male Mice under Physiological, but Not Immune-Challenged Conditions

open access: yesCells, 2021
Increasing evidence demonstrates that inflammatory cytokines—such as tumor necrosis factor (TNF)—are produced at low levels in the brain under physiological conditions and may be crucial for synaptic plasticity, neurogenesis, learning and memory.
Leda Mygind   +6 more
doaj   +1 more source

Propentofylline Prevents Sickness Behavior and Depressive-Like Behavior Induced by Lipopolysaccharide in Rats via Neuroinflammatory Pathway.

open access: yesPLoS ONE, 2017
Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate ...
Márcia M T Moraes   +8 more
doaj   +1 more source

Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways

open access: yesBMC Medicine, 2012
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Maes Michael   +6 more
doaj   +1 more source

Properties of the Sickness Questionnaire in an Australian sample with chronic medically unexplained symptoms

open access: yesBrain, Behavior, & Immunity - Health, 2020
Sickness behavior including malaise, fatigue and increased pain sensitivity is thought to be adaptive and facilitate recovery from disease. However, it may also reduce functioning and health if symptoms persists, which is why validated instruments for ...
Anna Andreasson   +6 more
doaj   +1 more source

Leading during change: the effects of leader behavior on sickness absence in a Norwegian health trust

open access: yesBMC Public Health, 2012
Background Organizational change often leads to negative employee outcomes such as increased absence. Because change is also often inevitable, it is important to know how these negative outcomes could be reduced.
Bernstrøm Vilde Hoff   +1 more
doaj   +1 more source

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