Results 21 to 30 of about 36,963 (195)
Basal and LPS-stimulated inflammatory markers and the course of depression and anxiety symptoms
Introduction Multiple studies show an association between inflammation –characterized by increased blood levels of C-reactive protein (CRP) and pro-inflammatory cytokines– and major depressive disorder (MDD).
W. A. Van Eeden
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The aim of this study was to determine (1) associations between workplace bullying and subsequent risk and duration of medically certified sickness absence, (2) whether employees’ perceptions of supportive, fair, and empowering leader behavior moderate ...
Morten Birkeland Nielsen +3 more
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Neuro-Inflammatory Response and Brain-Peripheral Crosstalk in Sepsis and Stroke
Despite recent therapeutic advances, ischemic stroke is still a leading cause of death and disability. There is renewed attention on peripheral inflammatory signaling as a way of modulating the post-ischemic neuro-inflammatory process.
Lena Bourhy +7 more
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Cytokine, Sickness Behavior, and Depression [PDF]
Sufficient evidence is now available to accept the concept that the brain recognizes cytokines as molecular signals of sickness. Clarifying the way the brain processes information generated by the innate immune system is accompanied by a progressive elucidation of the cellular and molecular components of the intricate system that mediates cytokine ...
openaire +5 more sources
Sickness behaviour: Causes and effects
This paper discusses sickness behavior as a central motivational state. It deals with the adaptational value and underlying mechanisms of sickness behavior and with the consequences of the body's failure to terminate the activity of the symptoms ...
M. Viljoen
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Increasing evidence demonstrates that inflammatory cytokines—such as tumor necrosis factor (TNF)—are produced at low levels in the brain under physiological conditions and may be crucial for synaptic plasticity, neurogenesis, learning and memory.
Leda Mygind +6 more
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Recent studies have demonstrated the intimate relationship between depression and immune disturbances. Aware of the efficacy limits of existing antidepressant drugs and the potential anti-inflammatory properties of propentofylline, we sought to evaluate ...
Márcia M T Moraes +8 more
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Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
It is of considerable translational importance whether depression is a form or a consequence of sickness behavior. Sickness behavior is a behavioral complex induced by infections and immune trauma and mediated by pro-inflammatory cytokines.
Maes Michael +6 more
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Sickness behavior including malaise, fatigue and increased pain sensitivity is thought to be adaptive and facilitate recovery from disease. However, it may also reduce functioning and health if symptoms persists, which is why validated instruments for ...
Anna Andreasson +6 more
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Background Organizational change often leads to negative employee outcomes such as increased absence. Because change is also often inevitable, it is important to know how these negative outcomes could be reduced.
Bernstrøm Vilde Hoff +1 more
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