Results 41 to 50 of about 21,544 (174)

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Distribution and Cycling of Siderophores in the Eastern North and Tropical Pacific Oceans

Geophysical Research Letters
Most iron (Fe) dissolved in seawater is complexed to organic ligands of unknown composition. Here we investigate the distribution of siderophores, small organic compounds synthesized by microbes to bind environmental Fe and facilitate its transport into ...
Jingxuan Li, Lydia Babcock‐Adams, Matthew R. McIlvin, Daniel J. Repeta   +3 more
doaj   +1 more source

Campylobacter chez les porcs biologiques et conventionnels: prévalence et antibiorésistance [PDF]

, 2014
Cette étude a pour objectif d’obtenir et comparer des données de prévalence et de résistance aux antibiotiques de Campylobacter isolés de porcs issus de la production biologique porcine et de la production conventionnelle.
CHIDAINE, Bérengère, DENIS, Martine, KEMPF, Isabelle, KEROUANTON, Annaëlle, ROSE, Valérie   +4 more
core  

Discovery of an Adaptive Neuroimmune Response Driving Itch and Fast Tick Removal with Implications for Preventing Pathogen Transmission

Advanced Science, EarlyView.
Doehl et al. discovered an adaptive neuroimmune mechanism that induces itch in tick‐exposed guinea pigs, enabling rapid tick removal. This itch‐induced tick removal (IITR) is mediated by an adaptive cellular immune response and is independent of IgG, IgE, or TRPV1.
Johannes S. P. Doehl, Tiago D. Serafim, Serena Doh, Charles S. Grugan, Eva Iniguez, Luana Rogerio, Ronja Frigard, Ranadhir Dey, Pedro Cecilio, Xinglong Gu, Pang‐Yen Tseng, Aline da Silva Moreira, Mahnaz Minai, James Oristian, Hans Ackerman, Steven Brooks, Caroline Percopo, Siu‐Ping Ng, Derron A. Alves, Lucas Tirloni, Jennifer M. Anderson, Adriana Marques, Fabiano Oliveira, Shaden Kamhawi, Daniel E. Sonenshine, José M. C. Ribeiro, Mark Hoon, Jesus G. Valenzuela   +27 more
wiley   +1 more source

Possible Mechanisms of Action of Two Pseudomonas fluorescens Isolates as Probiotics on Saprolegniosis Control in Rainbow Trout (Oncorhynchus mykiss Walbaum)

Animals, 2020
Probiotics have been proposed as one of the alternatives to the chemical treatments currently used in aquaculture. Recently, the possible usefulness of certain microorganisms, mainly bacteria, has been highlighted as a potential biocontrol for ...
Concepción González-Palacios, Juan-Miguel Fregeneda-Grandes, José-Miguel Aller-Gancedo   +2 more
doaj   +1 more source

Natural combinatorial genetics and prolific polyamine production enable siderophore diversification in Serratia plymuthica

BMC Biology, 2021
Background Iron is essential for bacterial survival. Bacterial siderophores are small molecules with unmatched capacity to scavenge iron from proteins and the extracellular milieu, where it mostly occurs as insoluble Fe3+.
Sara Cleto, Kristina Haslinger, Kristala L. J. Prather, Timothy K. Lu   +3 more
doaj   +1 more source

Harnessing microbial iron chelators to develop innovative therapeutic agents

Journal of Advanced Research, 2022
Background: Bacterial infections involving multidrug-resistant Gram-negative bacteria have become critically involved in the current antibiotic crisis.
Marta Ribeiro, Cátia A. Sousa, Manuel Simões   +2 more
doaj   +1 more source

Caractéristiques moléculaires de l'immunité des plantes induite par les rhizobactéries non pathogènes [PDF]

, 2008
Molecular characteristics of the rhizobacteria-triggered plant immunity. Recognition of certain non-pathogenic rhizobacteria by plants can trigger a systemic resistance reaction that renders the host less susceptible to subsequent infection by a virulent
Jourdan E., Ongena M., Thonart P.
core  

CsdA‐LaeB Regulatory Hub Contributes to Aspergillus fumigatus Virulence via Fumiquinazoline C Biosynthesis

Advanced Science, EarlyView.
This study identifies a conserved CsdA‐LaeB hub in Aspergillus fumigatus that regulates secondary metabolite fumiquinazoline C (FqC). Disrupting this hub enhances FqC production and virulence, shedding new light on the post‐transcriptional regulatory logic linking secondary metabolism to pathogenicity and offering alternative strategies for diagnostic ...
Zili Song, Hongjiao Zhang, Leixin Ye, Yuxin Lei, Linqi Wang, Xiao Liu, Nayanna M. Mercado Soto, Nancy P. Keller, Berl R. Oakley, Can Zhao, Michael Bromley, Hongwei Liu, Lei Cai, Koon Ho Wong, Wen‐Bing Yin   +14 more
wiley   +1 more source

Metarhizium anisopliaeMitigates the Phytotoxicity of Lead and Nanoplastics on Rice by Modifying Physiological, Transcriptomic, Metabolomic Activities, and Soil Microbiome

Advanced Science, EarlyView.
Metarhizium anisopliae alleviates the phytotoxic effects of polyethylene nanoplastics (NP) and lead (Pb) in rice by decreasing Pb uptake, restoring antioxidant and hormonal equilibrium, and promoting growth. Additionally, the fungus modifies the rhizosphere microbiota, enhancing both contaminant tolerance and plant growth, thereby effectively ...
Jing Peng, Qi Yan, Muhammad Umair Hassan, Muhammad Imran, Fasih Ullah Haider, Jianfeng Liang, Xingmin Wang, Shaukat Ali   +7 more
wiley   +1 more source