Results 91 to 100 of about 5,942,634 (324)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

TAMIS: Golden-Model-Free EM Trojan Detection via Temperature-Aware Multi-Instance Segmentation and Clustering

open access: yesIEEE Access
We present a Golden-Model-free framework for hardware Trojan (HT) detection that treats temperature not as noise to remove but as physical context that organizes electromagnetic (EM) variability.
Daehyeon Lee   +3 more
doaj   +1 more source

Kangaroos in Side-Channel Attacks [PDF]

open access: yes, 2015
Side-channel attacks are a powerful tool to discover the cryptographic secrets of a chip or other device but only too often do they require too many traces or leave too many possible keys to explore. In this paper we show that for side channel attacks on discrete-logarithm-based systems significantly more unknown bits can be handled by using Pollard's ...
Lange, T.   +2 more
openaire   +3 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

On the Security of Lightweight Homomorphic Obfuscation for Protecting Against Hardware Trojans

open access: yesTransactions on Cryptographic Hardware and Embedded Systems
Hardware Trojan (HT) attacks pose a critical threat to modern microelectronics by enabling the leakage of sensitive information, such as cryptographic keys, or by inducing functional faults.
Tanvir Hossain   +3 more
doaj   +1 more source

Trojan Side-Channels: Lightweight Hardware Trojans through Side-Channel Engineering [PDF]

open access: yes, 2009
The general trend in semiconductor industry to separate design from fabrication leads to potential threats from untrusted integrated circuit foundries. In particular, malicious hardware components can be covertly inserted at the foundry to implement hidden backdoors for unauthorized exposure of secret information.
Lin, L   +4 more
openaire   +2 more sources

DR.SGX: Hardening SGX Enclaves against Cache Attacks with Data Location Randomization

open access: yes, 2019
Recent research has demonstrated that Intel's SGX is vulnerable to software-based side-channel attacks. In a common attack, the adversary monitors CPU caches to infer secret-dependent data accesses patterns. Known defenses have major limitations, as they
Brasser, Ferdinand   +5 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Linear Precoding for Broadcast Channels with Confidential Messages under Transmit-Side Channel Correlation

open access: yes, 2013
In this paper, we analyze the performance of regularized channel inversion (RCI) precoding in multiple-input single-output (MISO) broadcast channels with confidential messages under transmit-side channel correlation.
Al-nahari, Azzam Y.   +3 more
core   +1 more source

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