Results 61 to 70 of about 1,586,399 (314)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Side-Channel Analysis of Chaos-Based Substitution Box Structures

open access: yesIEEE Access, 2019
There is a theoretically strong relationship between chaos and cryptology. In practice, one of the most successful applications of this relationship is chaos-based s-box structures.
Mehmet Sahin Acikkapi   +2 more
doaj   +1 more source

Exploring Feature Selection Scenarios for Deep Learning-based Side-channel Analysis

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2022
One of the main promoted advantages of deep learning in profiling sidechannel analysis is the possibility of skipping the feature engineering process.
Guilherme Perin   +2 more
doaj   +1 more source

Spatial Coding Techniques for Molecular MIMO

open access: yes, 2017
This paper studies spatial diversity techniques applied to multiple-input multiple-output (MIMO) diffusion-based molecular communications (DBMC). Two types of spatial coding techniques, namely Alamouti-type coding and repetition MIMO coding are suggested
Chae, Chan-Byoung   +3 more
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Side-Channel Analysis of the Xilinx Zynq UltraScale+ Encryption Engine

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2020
The Xilinx Zynq UltraScale+ (ZU+) is a powerful and flexible System-on- Chip (SoC) computing platform for next generation applications such as autonomous driving or industrial Internet-of-Things (IoT) based on 16 nm production technology. The devices are
Benjamin Hettwer   +4 more
doaj   +3 more sources

A Modular and Optimized Toolbox for Side-Channel Analysis

open access: yesIEEE Access, 2019
The aim of this paper is to describe the characteristics of a toolbox developed to carry out a side-channel analysis of cryptosystems implemented in physical devices.
Alberto Fuentes Rodriguez   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

open access: yesMolecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir   +2 more
wiley   +1 more source

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