Results 71 to 80 of about 24,883,380 (250)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Side-Channel Analysis of Chaos-Based Substitution Box Structures

IEEE Access, 2019
There is a theoretically strong relationship between chaos and cryptology. In practice, one of the most successful applications of this relationship is chaos-based s-box structures.
Mehmet Sahin Acikkapi, Fatih Ozkaynak, Ahmet Bedri Ozer   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Cloning Hardware Wallet Without Valid Credentials Through Side-Channel Analysis of Hash Function

IEEE Access
Hardware wallets, specialized devices designed to securely manage users’ credentials, play a crucial role in securing cryptocurrencies, ensuring credentials remain under user control without reliance on third-party entities.
Dongjun Park, Joonsup Kim, HeeSeok Kim, Seokhie Hong   +3 more
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

A Modular and Optimized Toolbox for Side-Channel Analysis

IEEE Access, 2019
The aim of this paper is to describe the characteristics of a toolbox developed to carry out a side-channel analysis of cryptosystems implemented in physical devices.
Alberto Fuentes Rodriguez, Luis Hernandez Encinas, Agustin Martin Munoz, Bernardo Alarcos Alcazar   +3 more
doaj   +1 more source

Template Attacks vs. Machine Learning Revisited (and the Curse of Dimensionality in Side-Channel Analysis)

, 2015
Template attacks and machine learning are two popular approaches to profiled side-channel analysis. In this paper, we aim to contribute to the understanding of their respective strengths and weaknesses, with a particular focus on their curse of ...
Markowitch, Olivier, Romain Poussier, François-Xavier Standaert, Standaert, François-Xavier, Liran Lerman, Olivier Markowitch, Lerman, Liran, 6th International Workshop on Constructive Side-Channel Analysis and Secure Design (COSADE 2015), Poussier, Romain, Bontempi, Gianluca, Gianluca Bontempi   +10 more
core   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source