Results 61 to 70 of about 792,245 (299)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Security of Side Channel Power Analysis Attack in Cloud Computing [PDF]

open access: yes, 2014
Future world is moving towards cloud computing In a word cloud computing can be defined as remote access computing resources through the Internet It provides a lot of services at a very low cost It can improve an organization s performance by ...
Nazrul Islam   +2 more
core  

Side-channel Analysis of Lightweight Ciphers: Does Lightweight Equal Easy? [PDF]

open access: yes, 2016
International audienceSide-channel attacks represent a powerful category of attacks against cryptographic devices. Still, side-channel analysis for lightweight ciphers is much less investigated than for instance for AES.
Sylvain Guilley   +7 more
core   +4 more sources

Deep Learning-based Side Channel Attack on HMAC SM3.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence, 2020
SM3 is a Chinese hash standard. HMAC SM3 uses a secret key to encrypt the input text and gives an output as the HMAC of the input text. If the key is recovered, adversaries can easily forge a valid HMAC.
Xin Jin   +3 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Thermal Side Channel Analysis [PDF]

open access: yes, 2020
Within a world that increasingly relies on connected devices, security and reliability have become more important then ever. Whereas failures in digital components used to have a limited effect, nowadays an attack on a critical digital infrastructure ...
Zwalua, Marc (author)
core  

Transitional Leakage in Theory and Practice

open access: yesTransactions on Cryptographic Hardware and Embedded Systems, 2022
Accelerated by the increased interconnection of highly accessible devices, the demand for effective and efficient protection of hardware designs against Side-Channel Analysis (SCA) is ever rising, causing its topical relevance to remain immense in both,
Nicolai Müller   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy