Results 91 to 100 of about 7,119,113 (404)

Modification of Poly(5,6-epoxy-l-norleucine) Gives Functional Polypeptides with Alternative Side-Chain Linkages. [PDF]

open access: yes, 2020
The preparation and characterization of a new epoxide containing polypeptide, poly(5,6-epoxy-l-norleucine), via postpolymerization modification of poly(l-homoallylglycine) is described.
Deming, Timothy J   +2 more
core  

Linear Rheological Response of a Series of Densely Branched Brush Polymers [PDF]

open access: yes, 2011
We have examined the linear rheological responses of a series of welldefined, dense, regularly branched brush polymers. These narrow molecular weight distribution brush polymers had polynorobornene backbones with degrees of polymerization (DP) of 200 ...
Grubbs, Robert H.   +4 more
core   +1 more source

Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359

open access: yesNature Communications, 2021
FR900359 (FR) is a Gq protein inhibitor depsipeptide isolated from an uncultivable plant endosymbiont and synthesized by non-ribosomal peptide synthetases.
Cornelia Hermes   +17 more
doaj   +1 more source

Two-sided bounds on the rate of convergence for continuous-time finite inhomogeneous Markov chains [PDF]

open access: yes, 2014
We suggest an approach to obtaining general two-sided bounds on the rate of convergence in terms of special "weighted" norms related to total variation. Some important classes of continuous-time Markov chains are considered: birth-death-catastrophes processes, queueing models with batch arrivals and group services, chains with absorption in zero.
arxiv   +1 more source

Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels

open access: yesScientific Reports, 2016
Gating charges in voltage-sensing domains (VSD) of voltage-sensitive ion channels and enzymes are carried on arginine side chains rather than lysine. This arginine preference may result from the unique hydration properties of the side chain guanidinium ...
Craig T. Armstrong   +3 more
semanticscholar   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Dynamics of end-pulled polymer translocation through a nanopore [PDF]

open access: yes, 2017
We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory to include ...
Ala-Nissila, Tapio   +3 more
core   +2 more sources

The solution supramolecular structure of α2 → 8 polysialic acid suggests a structural cause for its low immunogenicity

open access: yesFEBS Letters, EarlyView.
α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley   +1 more source

Side-chain and backbone ordering in Homopolymers [PDF]

open access: yesarXiv, 2006
In order to study the relation between backbone and side chain ordering in proteins, we have performed multicanonical simulations of deka-peptide chains with various side groups. Glu10, Gln10, Asp10, Asn10, and Lys10 were selected to cover a wide variety of possible interactions between the side chains of the monomers.
arxiv  

The Cytokinin Side Chain Commands Shooting [PDF]

open access: yesDevelopmental Cell, 2013
Functional distinction between structurally diverse cytokinins as essential plant hormones has remained enigmatic for decades. In this issue of Developmental Cell, Kiba et al. (2013) provide compelling evidence for the central role of CYP735A1/2 in synthesizing trans-hydroxylated cytokinins, which specify shoot growth, vital for energy and biomass ...
openaire   +3 more sources

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