Results 81 to 90 of about 7,119,113 (404)

The apo LETM1 F‐EF‐hand adopts a closed conformation that underlies a multi‐modal sensory role in mitochondria

open access: yesFEBS Letters, Volume 599, Issue 7, Page 971-988, April 2025.
We present the first solution structure of the Ca2+‐depleted LETM1 F‐EF‐hand through a D676A/N678A Ca2+ binding‐deficient mutant, revealing a closed hydrophobic cleft caused by a unique F1‐helix pivot. The apo LETM1 F‐EF‐hand exhibits regiospecific hot and cold unfolding, sensitivity to physiological pH changes and potential for promiscuous heterotypic
Qi‐Tong Lin   +2 more
wiley   +1 more source

Monte Carlo study of the ordering in a strongly frustrated liquid crystal [PDF]

open access: yesPhys. Rev. E 95, 062126 (2017), 2017
We have performed Monte Carlo simulations to investigate the temperature dependence of the ordering of the side chains of the X-shape liquid crystal molecules which are arranged in a hexagonal array. Each hexagon contains six side chains, one from each side of the hexagon. Each liquid crystal molecule has two, dissimilar, side chains, one that contains
arxiv   +1 more source

Theory of Side-Chain Liquid Crystal Polymers: Bulk Behavior and Chain Conformation [PDF]

open access: yes, 2010
We study the thermodynamics and chain conformation of side-chain liquid crystal polymers (SCLCPs) in the bulk using the self-consistent-field approach and a new model to account for the coupling between the orientation of the side-chain liquid-crystal ...
Wang, Rui, Wang, Zhen-Gang
core  

The two-sided exit problem for an additive functional of a time-inhomogeneous Markov chain [PDF]

open access: yesarXiv, 2023
We consider an additive functional driven by a time-inhomogeneous Markov chain with a finite state space. Our study focuses on the joint distribution of the two-sided exit time and the state of the driving Markov chain at the time of exit, given in terms of expectation operators.
arxiv  

Molecular dynamics simulations of single-component bottle-brush polymers with a flexible backbone under poor solvent conditions [PDF]

open access: yesJ. Phys.: Condens. Matter 25 (2013) 285105, 2013
Conformations of a single-component bottle-brush polymer with a fully flexible backbone under poor solvent conditions are studied by molecular-dynamics simulations, using a coarse-grained bead-spring model with side chains of up to N=40 effective monomers.
arxiv   +1 more source

Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones

open access: yesFEBS Letters, Volume 599, Issue 9, Page 1269-1284, May 2025.
Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley   +1 more source

Absolutely continuous energy bands and extended electronic states in an aperiodic comb-shaped nanostructure

open access: yes, 2014
The nature of electronic eigenstates and quantum transport in a comb-shaped Fibonacci nanostructure model is investigated within a tight-binding framework. Periodic linear chains are side-attached to a Fibonacci chain, giving it the shape of an aperiodic
Pal, Biplab
core   +1 more source

Efficient routes to epimerically-pure side-chain derivatives of lanosterol [PDF]

open access: yes, 2004
A technically simple route is described to individual epimers of side-chain derivatives of lanosterol (3-hydroxy-5-lanosta-8,24-diene). Epimerically pure 24,25-epoxy-, 24,25-dihydroxy- and 24-bromo-25-hydroxy-lanosterol have been prepared in good yield ...
Kavtaradze, Levan K.   +2 more
core   +2 more sources

Side-Chain-Induced Rigid Backbone Organization of Polymer Semiconductors through Semifluoroalkyl Side Chains.

open access: yesJournal of the American Chemical Society, 2016
While high-mobility p-type conjugated polymers have been widely reported, high-mobility n-type conjugated polymers are still rare. In the present work, we designed semifluorinated alkyl side chains and introduced them into naphthalene diimide-based ...
Boseok Kang   +5 more
semanticscholar   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

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