Results 111 to 120 of about 6,649,879 (302)

Backreaction effects on the matter side of Einstein's field equations

, 2015
Recently, we have derived a novel and compact expression for how perturbations in the matter fields of the cosmological fluid can lead to deviations from the standard Friedmann equations.
Floerchinger, Stefan, Tetradis, Nikolaos, Wiedemann, Urs Achim   +2 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Targeting HIV-related Medication Side Effects and Sentiment Using Twitter Data [PDF]

, 2014
We present a descriptive analysis of Twitter data. Our study focuses on extracting the main side effects associated with HIV treatments. The crux of our work was the identification of personal tweets referring to HIV.
Adrover, Cosme, Bodnar, Todd, Salathe, Marcel   +2 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Eruption of hemorrhagic bullae and vesicles

JAAD Case Reports, 2022
Sabah Osmani, BA, Jiasen Wang, MD, Hillary Elwood, MD, Therese A. Holguin, MD   +3 more
doaj   +1 more source

Brief report of efficacy and side effect profile of crossing over to modified-release capsules of methylphenidate in ADHD patients receiving other treatments: case series

Psychiatry and Clinical Psychopharmacology, 2017
OBJECTIVES: Stimulants are recommended as the first-line pharmacotherapy in attention deficit/hyperactivity disorder (ADHD). Methylphenidate (MPH) is the most used stimulant. Medikinet Retard has modified-release capsules of MPH (MRC-MPH).
Burcu Özbaran, Sezen Köse, Fevzi Tuna Ocakoğlu, Hakan Kayış, Ayşegül Satar, Uğur Tekin   +5 more
doaj   +1 more source

Subprime side effects in the federal funds market [PDF]

Mortgage loans ; Federal funds market (United States)
Daniel L. Thornton
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Assessment of side effects of venesection (phlebotomy) procedure in Iraqi patients presenting with erythrocytosis: single center experience

Iraqi Journal of Hematology, 2015
Background : Venesection or phlebotomy is generally considered to be a safe method, but occasionally adverse effects of varying severity may occur during or at the end of the procedure.
Eaman Marouf Muhammad, Raid Ahmed Alrubaye, Alaa Fadhil Alwan   +2 more
doaj