Results 71 to 80 of about 2,166,400 (310)

Prolactin Elevation Due to Sertraline Use in a Patient with Pituitary Adenoma: A Case Report

open access: yesAhi Evran Medical Journal
Antipsychotics are the drugs that most frequently cause prolactinemia among the psychiatric drug groups. When prolactin eleva tion is mentioned, it is generally considered as a side effect related to antipsychotics.
Meltem Puşuroğlu   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Gastrointestinal side effects of the radioiodine therapy for the patients with differentiated thyroid carcinoma two days after prescription

open access: yesWorld Journal of Nuclear Medicine, 2016
Iodine-131 (I-131) therapy is one of the conventional approaches in the treatment of patients with differentiated thyroid carcinoma (DTC). The radioiodine agents also accumulate in the other organs that cause pain and damage to the patients.
Mehran Pashnehsaz   +6 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Self-reported adverse effects as barriers to adherence to antiretroviral therapy in HIV-infected patients in Pretoria

open access: yesSouth African Family Practice, 2008
Background: Adherence is the key to the effectiveness of antiretroviral therapy. However, many factors have been identified as facilitating or hampering adherence.
Ntambwe G. Malangu
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Psychotropic Drugs and Ocular Side Effects

open access: yesTürk Oftalmoloji Dergisi, 2013
Nowadays the number of patients using the types of drugs in question here has significantly increased. A study carried out in relation with the long term use of psychotropic drugs shows that the consumption of this group of drugs has substantially ...
İpek Sönmez, Ümit Aykan
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Efficacy of opioid switching in asian 51-year-old-man with a phenomenon of pharmacokinetics tolerance: case report

open access: yesPathos, 2012
Opioid switching is a therapeutic procedure used in pain management as a method to improve analgesic response and/or reduce adverse side effects. The rationale behind opioid substitution is the incomplete cross-tolerance between opioid.
Carmelo Costa   +2 more
doaj  

Assessing the unwanted: A systematic review of instruments used to assess negative effects of psychotherapy

open access: yesBrain and Behavior, 2019
Objective While the efficacy of psychotherapy in the treatment of mental disorders is well examined, systematic research into negative effects of psychotherapy seems comparatively rare.
Philipp Herzog   +3 more
doaj   +1 more source

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