Results 81 to 90 of about 2,530,127 (316)

Auricular acupressure: reducing side effects of chemotherapy in women with ovarian cancer

open access: yes, 2019
Purpose: Many women with ovarian cancer may experience adverse effects from adjuvant chemotherapy after surgery. Non-pharmacological interventions can be used to reduce these side effects.
Tsao, Ying, Creedy, Debra K
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Negotiating side effects in follow-up appointments for hypertension

open access: yes, 2006
Hypertension is an important risk factor for cardiovascular disease, the incidence of which it is possible to reduce by prophylactic treatment with antihypertensive drugs.
Linell, Per,   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Side effect of cardiological drugs

open access: yes, 2021
Cardiological drugs are necessary for the treatment of the cardiological diseases such as hypertension, heart failure, arrhythmia, myocardial infarction and so on. But they have also side effects, ranging from mild to severe result.
Sunada, Shohei
core  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Efficacy of opioid switching in asian 51-year-old-man with a phenomenon of pharmacokinetics tolerance: case report

open access: yesPathos, 2012
Opioid switching is a therapeutic procedure used in pain management as a method to improve analgesic response and/or reduce adverse side effects. The rationale behind opioid substitution is the incomplete cross-tolerance between opioid.
Carmelo Costa   +2 more
doaj  

Side effects of anticovid19 vaccines

open access: yes, 2023
reservedIn questo elaborato, nel primo capitolo si andranno a discutere quali sono gli effetti collaterali dei 5 vaccini anti covid 19 maggiormente utilizzati in Italia.
BATTISTIN, MARIA
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Complete and efficient methods for supporting side effects in independent/restricted and-parallelism

open access: yes, 1989
It has been shown that it is possible to exploit Independent/Restricted And-parallelism in logic programs while retaining the conventional "don't know" semantics of such programs.
Muthukumar, Kalyan   +3 more
core  

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