Distribution of siderophore gene systems on a Vibrionaceae phylogeny: Database searches, phylogenetic analyses and evolutionary perspectives. [PDF]
Siderophores are small molecules synthesized and secreted by bacteria and fungi to scavenge iron. Extracellular ferri-siderohores are recognized by cognate receptors on the cell surface for transport over membranes.
Sunniva Katharina Thode +4 more
doaj +3 more sources
Gram-positive siderophore-shuttle with iron-exchange from Fe-siderophore to apo-siderophore by Bacillus cereus YxeB [PDF]
Small molecule iron-chelators, siderophores, are very important in facilitating the acquisition of Fe(III), an essential element for pathogenic bacteria. Many Gram-negative outer-membrane transporters and Gram-positive lipoprotein siderophore-binding proteins have been characterized, and the binding ability of outer-membrane transporters ...
Fukushima, Tatsuya +5 more
openaire +6 more sources
The design and synthesis of an antibacterial phenothiazine–siderophore conjugate
Siderophore–antibiotic conjugates consist of an antibiotic covalently linked by a tether to a siderophore. Such conjugates can demonstrate enhanced uptake and internalisation to the bacterial cell resulting in significantly reduced MIC values and ...
Abed Tarapdar +4 more
doaj +3 more sources
The Siderophore Metabolome of Azotobacter vinelandii [PDF]
ABSTRACT In this study, we performed a detailed characterization of the siderophore metabolome, or “chelome,” of the agriculturally important and widely studied model organism Azotobacter vinelandii . Using a new high-resolution liquid chromatography-mass spectrometry (LC-MS) approach, we found over 35 ...
Oliver, Baars +3 more
openaire +3 more sources
Recent advances in siderophore biosynthesis
The biosynthesis of the microbial small molecule iron scavengers known as siderophores has been of interest since their discovery in the middle of the past century. Two main pathways for siderophore biosynthesis exist. One is directed by a large family of modular multienzymes called non-ribosomal peptide synthetases (NRPSs) while the other is NRPS ...
Barry, Sarah M., Challis, Gregory L.
openaire +4 more sources
Siderophore-Mediated Mobilization of Manganese Limits Iron Solubility in Mixed Mineral Systems [PDF]
Recent laboratory and field studies show the need to consider the formation of aqueous Mn(III)-siderophore complexes in manganese (Mn) and iron (Fe) geochemical cycling, a shift from the historical view that aqueous Mn(III) species are unstable and thus ...
Peña, Jasquelin +3 more
core +1 more source
Production of siderophore type chelates by mixed bacterioplankton populations in nutrient enriched seawater incubations [PDF]
Siderophore type chelates were isolated from nutrient enriched seawater collected from coastal and near shore environments and detected using a novel high performance liquid chromatography – electrospray ionisation – mass spectrometric technique ...
McCormack, P. +9 more
core +1 more source
International audienceInspired by natural sideromycins, the conjugation of antibiotics to siderophores is an attractive strategy to facilitate "Trojan horse" delivery of antibiotics into bacteria.
Drobecq, Herve +11 more
core +1 more source
Siderophore-like molecules facilitate enhanced iron uptake.
Cultures of DSS3 cells that were grown in either low or high-iron media were able to acquire iron more effectively when supplemented with SLMs than cultures of DSS3 cells that were not supplemented with SLMs.
Gary R. LeCleir (4419937) +2 more
core +1 more source
Endophytic fungi from orchid plants are reported to secrete secondary metabolites which include bioactive antimicrobial siderophores. In this study endophytic fungi capable of secreting siderophores were isolated from Cymbidium aloifolium, a medicinal ...
Srinivas Chowdappa +4 more
doaj +1 more source

