Results 111 to 120 of about 21,364 (156)
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BioMetals, 2009
Siderophores are low molecular weight organic ligands exuded by some aerobic organisms and plants to acquire Fe under Fe-limited conditions. The hydroxamate siderophores may sorb to aluminosilicate clays through a variety of mechanisms depending upon the nature of the clay and of the siderophore along with solution conditions such as pH, ionic strength,
Patricia A, Maurice +2 more
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Siderophores are low molecular weight organic ligands exuded by some aerobic organisms and plants to acquire Fe under Fe-limited conditions. The hydroxamate siderophores may sorb to aluminosilicate clays through a variety of mechanisms depending upon the nature of the clay and of the siderophore along with solution conditions such as pH, ionic strength,
Patricia A, Maurice +2 more
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ChemInform, 2003
AbstractFor Abstract see ChemInform Abstract in Full Text.
E.A. Dertz, K.N. Raymond
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AbstractFor Abstract see ChemInform Abstract in Full Text.
E.A. Dertz, K.N. Raymond
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Microbial siderophore-mediated transport
Biochemical Society Transactions, 2002Microbial iron chelates, called siderophores, are synthesized by bacteria and fungi in response to low iron availability in the environment. The present review summarizes structural details of siderophore ligands with respect to their transport properties.
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Recent advances in siderophore biosynthesis
Current Opinion in Chemical Biology, 2009The biosynthesis of the microbial small molecule iron scavengers known as siderophores has been of interest since their discovery in the middle of the past century. Two main pathways for siderophore biosynthesis exist. One is directed by a large family of modular multienzymes called non-ribosomal peptide synthetases (NRPSs) while the other is NRPS ...
Barry, Sarah M., Challis, Gregory L.
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EcoSal Plus
ABSTRACT Siderophore cephalosporins are designed to exploit bacterial nutrient uptake systems to gain accelerated uptake across the outer membrane of Gram-negative bacteria. They contain iron (III) binding motifs that allow them to form complexes that will be recognized as potential substrates by iron-siderophore ...
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ABSTRACT Siderophore cephalosporins are designed to exploit bacterial nutrient uptake systems to gain accelerated uptake across the outer membrane of Gram-negative bacteria. They contain iron (III) binding motifs that allow them to form complexes that will be recognized as potential substrates by iron-siderophore ...
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Siderophore-dependent ferrichelatases
Iron is a crucial secondary metabolite for bacterial proliferation, but its bioavailability under infection conditions is limited by the low solubility of ferric ion and the host's ability to sequester iron by protein chelation. In these iron limiting conditions, bacteria produce and secrete low molecular weight ferric ion chelators, siderophores, to ...C E, Merrick +2 more
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Microbial siderophores: a mini review
Journal of Basic Microbiology, 2012AbstractIron is one of the major limiting factors and essential nutrients of microbial life. Since in nature it is not readily available in the preferred form, microorganisms produce small high affinity chelating molecules called siderophores for its acquisition. Microorganisms produce a wide variety of siderophores controlled at the molecular level by
Ratul, Saha +3 more
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Occurrence of Siderophores in Enterococci
Zentralblatt für Bakteriologie, 2000In 70 strains of the genus Enterococcus belonging to 16 species and isolated from clinical material, animals and the environment, a hydroxamic class of siderophores was detected with the aid of chemical and biological tests. A correlation between siderophore activity and species affiliation was found: E.
P, Lisiecki, P, Wysocki, J, Mikucki
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Modular Fluorescent-Labeled Siderophore Analogues
Journal of Medicinal Chemistry, 1998Biomimetic analogues 1 of the microbial siderophore (iron carrier) ferrichrome were labeled via piperazine with various fluorescent markers at a site not interfering with iron binding or receptor recognition (compounds 10-12). These iron carriers were built from a tetrahedral carbon symmetrically extended with three strands, each containing an amino ...
R, Nudelman +5 more
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Cefiderocol: a novel siderophore cephalosporin
Expert Opinion on Investigational Drugs, 2018The emergence of multidrug-resistant bacterial pathogens has led to a global public health emergency and novel therapeutic options and drug-delivery systems are urgently needed. Cefiderocol is a siderophore cephalosporin antibiotic that has recently been developed to combat a variety of bacterial pathogens, including β-lactam- and carbapenem-resistant ...
Justin J, Choi, Matthew W, McCarthy
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