Results 141 to 150 of about 7,711,295 (297)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Reflections [Complete issue: February - March 1979, vol 5] [PDF]
, 1978 Publishing History: Print issues of Reflections magazine were published from 1975 to 1999 and its successor, Reflections on Nursing Leadership (RNL) began publication in 2000.
Sigma Theta Tau International +1 more
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Anomalies in family unification models from bordism classification
Journal of High Energy PhysicsWe study anomalies in family unification models within the framework of the bordism classification of invertible field theories. These models are based on four-dimensional N $$ \mathcal{N} $$ = 1 supersymmetric nonlinear sigma models, in which the three ...
Tsubasa Sugeno, Hiroki Wada
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Creating Healthy Work Environments 2017 Conference Proceedings [PDF]
, 2018 The Honor Society of Nursing, Sigma Theta Tau International (STTI) conducted its 2017 Creating Healthy Work Environments conference from 17 March through 19 March in Indianapolis, Indiana, USA, with the theme of Best Practices in Clinical and Academic ...
Sigma Theta Tau International
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Arista3 report executive summary: Nurses and health, a global future [PDF]
, 2003 Now completed, the Arista series, an initiative of the Honor Society of Nursing, Sigma Theta Tau International, was designed to bring the best thinking to bear in confronting health issues of global significance, providing a multinational ...
Sigma Theta Tau International
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Reflections [Complete issue : 1986 April - May], Vol 10 [PDF]
, 1984 Publishing History: Print issues of Reflections magazine were published from 1975 to 1999 and its successor, Reflections on Nursing Leadership (RNL) began publication in 2000.
Sigma Theta Tau International
core