Results 81 to 90 of about 2,430,073 (342)
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Testing dark energy models in the light of $$\sigma _8$$ σ8 tension
European Physical Journal C: Particles and Fields, 2019 It has been pointed out that there exists a tension in $$\sigma _8-\varOmega _m$$ σ8-Ωm measurement between CMB and LSS observation. In this paper we show that $$\sigma _8-\varOmega _m$$ σ8-Ωm observations can be used to test the dark energy theories. We
Gaetano Lambiase +3 more
doaj +1 more source
Universal 1-loop divergences for integrable sigma models
Journal of High Energy Physics, 2023 We present a simple, new method for the 1-loop renormalization of integrable σ-models. By treating equations of motion and Bianchi identities on an equal footing, we derive ‘universal’ formulae for the 1-loop on-shell divergences, generalizing case-by ...
Nat Levine
doaj +1 more source
Research on Rockburst Classification Prediction Based on BP-SVM Model
IEEE Access, 2022 Rockburst is a complex destabilization phenomenon which is a combination of multiple factors, the study of rockburst for classification prediction can help prevent and control engineering geological hazards, reduce casualties and property damage.
Jiang Guo +3 more
doaj +1 more source
Supersymmetric Sigma Model Geometry [PDF]
Symmetry, 2012 This is a review of how sigma models formulated in Superspace have become important tools for understanding geometry. Topics included are: The (hyper)kähler reduction; projective superspace; the generalized Legendre construction; generalized Kähler geometry and constructions of hyperkähler metrics on Hermitian symmetric spaces.
openaire +4 more sources
Supersymmetry-Breaking Nonlinear Sigma Models [PDF]
, 2012 We consider a novel class of constraints on chiral superfields to obtain supersymmetric nonlinear sigma models in four spacetime dimensions, which strictly combine the internal symmetry breaking with spontaneous supersymmetry breaking.
Imai, Takumi +2 more
core +2 more sources
Universality of a truncated sigma-model
Physics Letters B, 2022 Bosonic quantum field theories, even when regularized using a finite lattice, possess an infinite dimensional Hilbert space and, therefore, cannot be simulated in quantum computers with a finite number of qubits. A truncation of the Hilbert space is then needed and the physical results are obtained after a double limit: one to remove the truncation and
Andrei Alexandru +3 more
openaire +3 more sources
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Journal of High Energy Physics, 2019 We consider a class of ansätze for the construction of exact solutions of the Einstein-nonlinear σ-model system with an arbitrary cosmological constant in (3+1) dimensions.
Alex Giacomini, Marcello Ortaggio
doaj +1 more source
FEBS Letters, EarlyView.Spot‐14 and Spot‐14R play distinct roles in regulating metabolism in brown and beige adipocytes. While both influence lipid and glucose pathways, Spot‐14 uniquely controls thermogenic gene expression. This dual regulation balances energy storage and heat production, highlighting potential therapeutic targets for obesity and metabolic disorders. Spot 14
Lidia Itzel Castro‐Rodríguez +3 more
wiley +1 more source