Results 111 to 120 of about 5,116,497 (296)
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Regarding Sigma Phase Formation [PDF]
David S. Bloom, Nicholas J. Grant
openaire +1 more source
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Effect of V doping on the phase structure of FeCrNiMnV
This study utilized the CALPHAD method to establish a thermodynamic calculation model for high-entropy alloy FeCrNiMnVx (x=0.0~1.0) and conducted in-depth discussions and analysis on the phase composition and strength of FeCrNiMnVx with V doping.The ...
WANG Jun +5 more
doaj
Influence of Copper Addition on Sigma Phase Precipitation during Hot Deformation of Duplex Steel. [PDF]
Stradomski G, Szarek A, Rydz D.
europepmc +1 more source
Topological Terms and Phases of Sigma Models
5 pages, comments welcome!
openaire +2 more sources
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Influencia de la fase sigma en la laminación en frío de los aceros inoxidables dúplex
One of the steps in the industrial rolling process of duplex stainless steels is the annealing heat treatment after hot rolling. If this annealing is performed in a temperature range that favours the precipitation of intermetallic phases, the mechanical ...
Fargas, G., Mateo, A., Anglada, M.
doaj
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source

