Results 111 to 120 of about 1,674,719 (294)

Gradient Distribution of Microstructures and Mechanical Properties in a FeCoCrNiMo High-Entropy Alloy during Spark Plasma Sintering

open access: yesMetals, 2019
A novel graded material of a high-entropy alloy (HEA) FeCoCrNiMo was fabricated by spark plasma sintering (SPS) processing. After SPS, the HEA specimens consisted of a single face-centred cubic (FCC) phase in the center, but dual FCC and a tetragonal ...
Mingyang Zhang   +6 more
doaj   +1 more source

The sigma-Phase Ta2Al. [PDF]

open access: yesActa Chemica Scandinavica, 1960
Lars-Erik Edshammar   +3 more
openaire   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata   +10 more
wiley   +1 more source

Elastic model for stress–tensor-induced martensitic transformation and lattice instability in silicon under large strains

open access: yesMaterials Research Letters, 2017
Recent molecular dynamics simulations for phase transformations (PTs) Si I $ \leftrightarrow $ Si II under multiaxial loading revealed that lattice instability criteria for Si I $ \leftrightarrow $ Si II PTs are linear in the stresses $ \sigma _i ...
Valery I. Levitas
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Influencia de la fase sigma en la laminación en frío de los aceros inoxidables dúplex

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2004
One of the steps in the industrial rolling process of duplex stainless steels is the annealing heat treatment after hot rolling. If this annealing is performed in a temperature range that favours the precipitation of intermetallic phases, the mechanical ...
Fargas, G., Mateo, A., Anglada, M.
doaj  

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