Results 101 to 110 of about 5,116,497 (296)

EBSD spatial resolution for detecting sigma phase in steels

open access: yesUltramicroscopy, 2016
The spatial resolution of the electron backscatter diffraction signal is explored by Monte Carlo simulation for the sigma phase in steel at a typical instrumental set-up. In order to estimate the active volume corresponding to the diffracted electrons, the fraction of the backscattered electrons contributing to the diffraction signal was inferred by ...
Fernandez Bordin, Santiago Pablo   +3 more
openaire   +3 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

A minimalistic pure spinor sigma-model in AdS

open access: yesJournal of High Energy Physics, 2018
The b-ghost of the pure spinor formalism in a general curved background is not holomorphic. For such theories, the construction of the string measure requires the knowledge of the action of diffeomorphisms on the BV phase space.
Andrei Mikhailov
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Gradient Distribution of Microstructures and Mechanical Properties in a FeCoCrNiMo High-Entropy Alloy during Spark Plasma Sintering

open access: yesMetals, 2019
A novel graded material of a high-entropy alloy (HEA) FeCoCrNiMo was fabricated by spark plasma sintering (SPS) processing. After SPS, the HEA specimens consisted of a single face-centred cubic (FCC) phase in the center, but dual FCC and a tetragonal ...
Mingyang Zhang   +6 more
doaj   +1 more source

The sigma-Phase Ta2Al. [PDF]

open access: yesActa Chemica Scandinavica, 1960
Lars-Erik Edshammar   +3 more
openaire   +1 more source

On the formation of stripe, sigma, and honeycomb phases in a core–corona system

open access: yesSoft Matter, 2017
Using Monte Carlo simulations and free-energy calculations, we investigate the phase behaviour of a two-dimensional core-corona system. We model this system as particles consisting of an impenetrable hard core of diameter σHD surrounded by a purely repulsive soft corona of diameter δ = 1.95σHD.
Harini Pattabhiraman, Marjolein Dijkstra
openaire   +3 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Resource paper and position statement on: Leadership and leadership development priorities [PDF]

open access: yes, 2005
The Honor Society of Nursing, Sigma Theta Tau International has long recognized and supported the importance of leadership and leadership development in the nursing profession.
Sigma Theta Tau International
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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