Results 241 to 250 of about 820,649 (291)

Sustainable Catalyst‐Free PLG Networks: Recyclability, Biodegradability, and Functional Performance

Advanced Functional Materials, EarlyView.
A catalyst‐additive free covalent adaptable network is developed from star‐shaped poly(lactide‐co‐glycolide) cross‐linked with pyromellitic dianhydride, enabling internal carboxylic acid‐driven transesterification. The resulting biodegradable network exhibits mechanical robustness (Young's modulus ≈1.6 GPa), complete recyclability, rapid biodegradation
Lars Schwarzer, Emilia Fulajtar, Seema Agarwal   +2 more
wiley   +1 more source

Pharmacological Effects of .SIGMA.-Receptor Ligands. Atypical antipsychotic profiles of sigma receptor ligands.

Folia Pharmacologica Japonica, 1999
openaire   +2 more sources

ATP-related purinergic signaling via P2Y12 contributes to airway epithelial barrier integrity. [PDF]

BMC Mol Cell Biol
Tsuya K, Maruoka S, Okamoto S, Shikano S, Ujike M, Yamada S, Kurosawa Y, Mizumura K, Kozu Y, Gon Y.   +9 more
europepmc   +1 more source

Heavy alcohol consumption attenuates human mesenteric artery responsiveness to sigma receptor-1 ligands. [PDF]

Am J Physiol Heart Circ Physiol
Zamora Diaz P, Le TQ, Hurtado Osorio L, McQueen JF, Bloom CA, Zimmermann Rollin I, Venkitasubramony V, Santiago LE, Chang M, Breslin JW.   +9 more
europepmc   +1 more source

Auxiliary TARP Subunits Define AMPA Receptor Pharmacology and Function. [PDF]

J Xenobiot
Bdir S, Çapan İ, Hawash M, Servi S, Qneibi M.   +4 more
europepmc   +1 more source

Psychedelic Therapies for Comorbid Major Depressive Disorder and Chronic Pain: A Review of Putative Mechanisms of Action. [PDF]

Pharmacol Res Perspect
Kazdan J, Ladha KS, Husain MI.
europepmc   +1 more source

Behavioral Domain-Specific Effects of Positive Modulation of α5 and α6 GABA_A Receptors in a Rat Double-Hit Stress Model. [PDF]

Pharmacol Res Perspect
Đorović Đ, Aranđelović J, Ivanović J, Jezdić K, Batinić B, Sharmin D, Mondal P, Cook JM, Savić MM.   +8 more
europepmc   +1 more source

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Sigma receptors: biology and therapeutic potential

Psychopharmacology, 2004
More than 20 years after the identification of the sigma receptors as a unique binding site in the brain and in the peripheral organs, several questions regarding this receptor are still open. Only one of the subtypes of the receptor has been cloned to date, but the endogenous ligand still remains unknown, and the possible association of the receptor ...
Xavier, Guitart, Xavier, Codony, Xavier, Monroy   +2 more
openaire   +4 more sources

Sigma Receptors – Literature Review

Journal of Diseases Disorders & Treatments, 2022
The paper reviewed data confirming that sigma1 receptors modulate NMDA neurotransmission. It has been established that they can enhance the spontaneous release of glutamate in the hippocampus, potentiate the release of a neurotrophic factor induced by glutamate, and also participate in the processes of synaptic restructuring (facilitation of long-term ...
Lizaveta IB, Lychkovskaya MA, Kudyan IA, Kudyan MG   +3 more
openaire   +1 more source

Sigma Receptors and Cocaine Abuse

Current Topics in Medicinal Chemistry, 2011
Sigma receptors have been well documented as a protein target for cocaine and have been shown to be involved in the toxic and stimulant actions of cocaine. Strategies to reduce the access of cocaine to sigma receptors have included antisense oligonucleotides to the sigma-1 receptor protein as well as small molecule ligand with affinity for sigma ...
Sanju, Narayanan, Christophe, Mesangeau, Jacques H, Poupaert, Christopher R, McCurdy   +3 more
openaire   +2 more sources