Results 11 to 20 of about 29,210 (261)

Reshaping study design for faster extrapolation-based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN-NASPGHAN position paper. [PDF]

J Pediatr Gastroenterol Nutr
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Turner D, Assa A, Malham M, Bar-Asher SY, Rayan C, Hyams JS, Uhlig HH, Pasternak B, Wilson DC, Michel HK, de Ridder L, Zuckerman E, Aloi M, Szitanyi P, Dubinsky MC, Griffiths AM, Saldana R, Martín-de-Carpi J, Wine E, Russell RK, Adler J, Picoraro J.   +21 more
europepmc   +2 more sources

Examining colorectal cancer screening uptake and health provider recommendations among underserved middle aged and older African Americans [PDF]

Health Promotion Perspectives, 2022
Background: The purpose of this study is to determine whether underserved middle-aged and older African Americans are receiving a colorectal cancer (CRC) screening test (sigmoidoscopy or colonoscopy) and if recommended by their provider. Additionally, we
Sharon Cobb, Tavonia Ekwegh, Edward Adinkrah, Hoorolnesa Ameli, Attallah Dillard, Lucy W. Kibe, Mohsen Bazargan   +6 more
doaj   +1 more source

Full colonoscopy in patients under 50 years old with lower gastrointestinal bleeding

Journal of Research in Medical Sciences, 2018
Background: Lower gastrointestinal (GI) bleeding is a common clinical problem in young patients. The management of this disease in patients is challenging.
Mahsa Khodadoostan, Ahmad Shavakhi, Reihaneh Padidarnia, Alireza Shavakhi, Mehdi Ahmadian   +4 more
doaj   +1 more source

Lower participation among immigrants in colorectal cancer screening in Norway

Frontiers in Public Health, 2023
IntroductionOrganized cancer screening programs should be equally accessible for all groups in society. We assessed differences in participation in colorectal cancer (CRC) screening among different immigrant groups.MethodsBetween 2012 and 2019, 140,000 ...
Sameer Bhargava, Sameer Bhargava, Edoardo Botteri, Edoardo Botteri, Mona Berthelsen, Nadia Iqbal, Kristin Ranheim Randel, Øyvind Holme, Øyvind Holme, Paula Berstad   +9 more
doaj   +1 more source

A positive SeHCAT test results in fewer subsequent investigations in patients with chronic diarrhoea. [PDF]

, 2017
Chronic diarrhoea is a common condition, resulting from a number of different disorders. Bile acid diarrhoea, occurring in about a third of these patients, is often undiagnosed.
Appleby, RN, Pattni, SS, Turner, JM, Walters, JR   +3 more
core   +1 more source

Is whole-colon investigation by colonoscopy, computerised tomography colonography or barium enema necessary for all patients with colorectal cancer symptoms, and for which patients would flexible sigmoidoscopy suffice? A retrospective cohort study

Health Technology Assessment, 2017
Background: For patients referred to hospital with suspected colorectal cancer (CRC), it is current standard clinical practice to conduct an examination of the whole colon and rectum.
Wendy Atkin, Kate Wooldrage, Urvi Shah, Kate Skinner, Jeremy P Brown, Willie Hamilton, Ines Kralj-Hans, Michael R Thompson, Karen G Flashman, Steve Halligan, Siwan Thomas-Gibson, Margaret Vance, Amanda J Cross   +12 more
doaj   +1 more source

A prospective multiple case study of the impact of emerging scientific evidence on established colorectal cancer screening programs: a study protocol. [PDF]

, 2012
BackgroundHealth-policy decision making is a complex and dynamic process, for which strong evidentiary support is required. This includes scientifically produced research, as well as information that relates to the context in which the decision takes ...
Dobrow, Mark J, Geddie, Hannah, Hoch, Jeffrey S, Rabeneck, Linda   +3 more
core   +1 more source

Volvulus

Journal of Education and Teaching in Emergency Medicine, 2017
History of present illness: A 26-year-old previously healthy female presented to the emergency department (ED) with diffuse abdominal pain, distention, and constipation for two days. Her physical exam was normal except for a soft, distended abdomen with
Sari Lahham, Kathryn Bennett, Mohammad Helmy   +2 more
doaj   +1 more source

K-ras and p53 mutations in colonic lavage fluid of patients with colorectal neoplasias [PDF]

, 2001
Background: The adenoma-carcinoma sequence has its molecular basis in several gene mutations of which K-ras and p53 are of paramount importance. The aims of this study were to evaluate whether these genetic alterations can be detected in colonic lavage ...
Folwaczny, Christian, Heinzlmann, M., Heldwein, W., Neynaber, S.   +3 more
core   +1 more source

Endoscopic scores for inflammatory bowel disease in the era of 'mucosal healing'. old problem, new perspectives [PDF]

, 2016
The importance of the endoscopic evaluation in inflammatory bowel disease (IBD) management has been recognized for many years. However, the modalities for reporting endoscopic activity represent an ongoing challenge.
Corleto, Vito Domenico, DELLE FAVE, Gianfranco, Desideri, F, DI GIULIO, Emilio, Menasci, F, Pagnini, C   +5 more
core   +1 more source