Results 21 to 30 of about 44,643 (219)

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho   +7 more
wiley   +1 more source

Existence of radial sign-changing solution for a fractional autonomous Kirchhoff equation

open access: yes四川大学学报. 自然科学版, 2020
The existence of sign-changing solutions for a fractional autonomous Kirchhoff equation is considered in the whole space. We prove that this equation is equivalent to a fractional autonomous Schr&odinger system under appropriate conditions.
ZHANG Dan-dan, DING Ling
doaj  

The Existence of the Sign-Changing Solutions for the Kirchhoff-Schrödinger-Poisson System in Bounded Domains

open access: yesAdvances in Mathematical Physics, 2020
In this paper, we study a class of the Kirchhoff-Schrödinger-Poisson system. By using the quantitative deformation lemma and degree theory, the existence result of the least energy sign-changing solution u0 is obtained.
Cun-bin An, Jiangyan Yao, Wei Han
doaj   +1 more source

Experience With Performing Rheocarna Therapy via the Single‐Needle Method for Treatment of Chronic Limb‐Threatening Ischemia

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This study investigated the safety and efficacy of single‐needle Rheocarna therapy for chronic limb‐threatening ischemia (CLTI) with wounds. Methods Six patients with CLTI involving ulcers unresponsive to revascularization underwent single‐needle Rheocarna treatment.
Yasutaka Yamauchi   +9 more
wiley   +1 more source

A minmax principle, index of the critical point, and existence of sign-changing solutions to elliptic boundary value problems

open access: yesElectronic Journal of Differential Equations, 1998
In this article we apply the minmax principle we developed in [6] to obtain sign-changing solutions for superlinear and asymptotically linear Dirichlet problems.
Alfonso Castro   +2 more
doaj  

Ground state sign-changing solutions and infinitely many solutions for fractional logarithmic Schrödinger equations in bounded domains

open access: yesElectronic Journal of Qualitative Theory of Differential Equations, 2021
We consider a class of fractional logarithmic Schrödinger equation in bounded domains. First, by means of the constraint variational method, quantitative deformation lemma and some new inequalities, the positive ground state solutions and ground state ...
Yonghui Tong   +2 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

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