Results 131 to 140 of about 1,195,588 (315)
Lost in translation: the problems of using mainstream MT evaluation metrics for sign language translation [PDF]
, 2006 In this paper we consider the problems of applying corpus-based techniques to minority languages that are neither politically recognised nor have a formally accepted writing system, namely sign languages.
Morrissey, Sara +3 more
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, 2021 Signs Becoming Signs evinces a broad, transdisciplinary perspective based on the thinking of Charles Sanders Peirce. In an effort to account for our knowledge of a universe open to an infinity of interpretations, the author dissolves many of the age-old dichotomies of Western thought into complementarities, which are qualified by a pair of Peirce's key
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
SLAMF7 defines subsets of human effector CD8 T cells
Scientific ReportsLong-term control of viral replication relies on the efficient differentiation of memory T cells into effector T cells during secondary immune responses.
Hassen Kared +11 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The relationship between deaf and hard of hearing students' Japanese Sign Language and Japanese Language Proficiency [PDF]
, 2009 The present study represents an attempt to investigate the relationship between Japanese Sign Language proficiency and the Japanese literacy skills of high school students who are deaf or hard or hearing (D/HH). A Pilot Test of Japanese Sign Language was
Fordyce, Mariela
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Dicta-Sign - Use of a Multilingual Corpus to Improve Sign Language Technology [PDF]
, 2010 International audienceDicta-Sign is a three-year EU-funded research project which started in January 2009. It aims to improve online communication for Deaf people by promoting the development of sign language based web applications.
Worseck, Satu +12 more
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