Results 121 to 130 of about 1,195,588 (315)

A Sign is Just a Sign

open access: yes, 2021
Signs are the basis of all communication. Semiotics—the study of signs—has increasingly become an area of intellectual inquiry, and the word itself is now even known to the general public, thanks to the popularity ofnovels by David Lodge and the fame of Umberto Eco. No one has done more to advance the study of signs than Thomas A. Sebeok.
openaire   +2 more sources

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Development of a GPS-Based Sign Inventory Tool for Iowa’s Statewide Management System, May 2011 [PDF]

open access: yes, 2011
This report is on state-of-the-art research efforts specific to infrastructure inventory/data collection with sign inventory as a case study. The development of an agency-wide sign inventory is based on feature inventory and location information ...

core  

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Welcome to Sanpete road sign [PDF]

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Sanpete County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by
Road Commission. Department of Highways
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Hotel Fremont & Casino road sign [PDF]

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Kane County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by ...
Road Commission. Department of Highways
core  

Phagocytosis of particulate antigens - all roads lead to calcineurin/NFAT signaling pathway

open access: yesFrontiers in Immunology, 2014
Jan eFric   +2 more
doaj   +1 more source

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

open access: yesScientific Reports, 2017
Large molecular complexes known as inflammasomes regulate the release of IL-1β from immune cells in response to infection and injury. Salmonella typhimurium infection is reported to activate NLRP3 and NLRC4 inflammasomes which are subsequently involved ...
Catherine E. Diamond   +5 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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