Results 101 to 110 of about 1,195,588 (315)
Nature Communications, 2016 The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental ...
Jinmiao Chen +4 more
doaj +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
, 1965 Scenic 89 tourism road sign photographed along Highway 89 in Davis County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by ...
Road Commission. Department of Highways
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
U24 Scenic Shortcut road sign [PDF]
, 1965 Utah Highway 24 road sign photographed along Highway 89 in Sevier County as part of a project by the State Departmetn of Highways to document Utah highways signs.This series contains outdoor advertising sign inventories conducted by the Department of ...
Road Commission. Department of Highways
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
A New Evaluation Approach for Sign Language Machine Translation [PDF]
, 2009 This paper proposes a new evaluation approach for sign language machine translation (SLMT). It aims to show a better correlation between its automatically generated scores and human judgements of translation accuracy.
Wald, Mike +2 more
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Genome Medicine, 2017 Background Expression quantitative trait loci (eQTL) databases represent a valuable resource to link disease-associated SNPs to specific candidate genes whose gene expression is significantly modulated by the SNP under investigation.
Dilip Kumar +33 more
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Utahhybrid Corn Seed road sign [PDF]
, 1965 Utahybrid Corn Seed road sign photographed along Highway 89 in Davis County as part of a project by the State Department of Highways to document Utah highway signs.This series contains outdoor advertising sign inventories conducted by the Department of ...
Road Commission. Department of Highways
core