Results 81 to 90 of about 1,373,326 (296)

Mpath maps multi-branching single-cell trajectories revealing progenitor cell progression during development

open access: yesNature Communications, 2016
The tools for constructing cell lineages from single cell data are limited. Here, the authors present Mpath: an algorithm to derive multi-branching trajectories using neighbourhood-based cell state transitions, and use this to predict developmental ...
Jinmiao Chen   +4 more
doaj   +1 more source

Border Store road sign

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Kane County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by ...
Road Commission. Department of Highways
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Sign is Just a Sign

open access: yes, 2021
Signs are the basis of all communication. Semiotics—the study of signs—has increasingly become an area of intellectual inquiry, and the word itself is now even known to the general public, thanks to the popularity ofnovels by David Lodge and the fame of Umberto Eco. No one has done more to advance the study of signs than Thomas A. Sebeok.
openaire   +2 more sources

Salina Drug road sign

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Sevier County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by ...
Road Commission. Department of Highways
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Gunnison City road sign

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Sanpete County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by
Road Commission. Department of Highways
core   +1 more source

An example-based approach to translating sign language [PDF]

open access: yes, 2005
Users of sign languages are often forced to use a language in which they have reduced competence simply because documentation in their preferred format is not available.
Morrissey, Sara   +3 more
core   +2 more sources

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Branch Motel road sign

open access: yes, 1965
Scenic 89 tourism road sign photographed along Highway 89 in Sevier County as part of a project by the State Department of Highways to document Utah highways signs.4 inches x 5 inchesThis series contains outdoor advertising sign inventories conducted by ...
Road Commission. Department of Highways
core   +1 more source

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