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The Interpreters' Newsletter 19, Sign Language Interpreting
, 2014 This issue of The Interpreters’ Newsletter aims to address a number of topics of interest in this growing area of Interpreting Studies presented in the form of discussion on prevailing situations, personal impressions on the profession (e.g.
Schaumberger Elke, Freelance Sign Language interpreter +12 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
, 1965 Scenic 89 tourism road sign photographed along Highway 89 in Kane County as part of a project by the State Department of Highways to document Utah highways signs.This series contains outdoor advertising sign inventories conducted by the Department of ...
Road Commission. Department of Highways
core +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Ergonomic assessment of kitchen workspace demands among older adults in India
Discover Public HealthIndian kitchens remain physically demanding environments for older adults, who routinely perform labour-intensive tasks such as kneading, chopping, grinding, stirring, and utensil washing.
Soumya Kanti Deb, S. Saleem Ahmed
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Synchronizing eye tracking and optical motion capture: How to bring them together
Journal of Eye Movement Research, 2018 Both eye tracking and motion capture technologies are nowadays frequently used in human sciences, although both technologies are usually used separately.
Birgitta Burger +2 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source