Results 31 to 40 of about 4,685,588 (297)

Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway

Nature Communications, 2020
Aging is associated with immune attrition that may impact the effectiveness of the immune system to protect the host from pathogens. Here the authors show that immune aging is associated with alterations in the Wnt/β-catenin signaling and reduced stem ...
Hassen Kared, Shu Wen Tan, Mai Chan Lau, Marion Chevrier, Crystal Tan, Wilson How, Glenn Wong, Marie Strickland, Benoit Malleret, Amanda Amoah, Karolina Pilipow, Veronica Zanon, Naomi Mc Govern, Josephine Lum, Jin Miao Chen, Bernett Lee, Maria Carolina Florian, Hartmut Geiger, Florent Ginhoux, Ezequiel Ruiz-Mateos, Tamas Fulop, Reena Rajasuriar, Adeeba Kamarulzaman, Tze Pin Ng, Enrico Lugli, Anis Larbi   +25 more
doaj   +1 more source

Signs Becoming Signs

, 2021
Signs Becoming Signs evinces a broad, transdisciplinary perspective based on the thinking of Charles Sanders Peirce. In an effort to account for our knowledge of a universe open to an infinity of interpretations, the author dissolves many of the age-old dichotomies of Western thought into complementarities, which are qualified by a pair of Peirce's key
openaire   +2 more sources

The Inflammasome Adaptor ASC Intrinsically Limits CD4+ T-Cell Proliferation to Help Maintain Intestinal Homeostasis

Frontiers in Immunology, 2019
The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis—a form of cell death induced by various pathogenic bacteria.
Hanif Javanmard Khameneh, Keith Weng Kit Leong, Andrea Mencarelli, Maurizio Vacca, Bezaleel Mambwe, Bezaleel Mambwe, Kurt Neo, Alice Tay, Francesca Zolezzi, Bernett Lee, Alessandra Mortellaro, Alessandra Mortellaro   +11 more
doaj   +1 more source

Discourses Of Prejudice In The professions: The Case Of Sign Languages [PDF]

, 2017
There is no evidence that learning a natural human language is cognitively harmful to children. To the contrary, multilingualism has been argued to be beneficial to all.
Humphries, T., Kushalnagar, P., Mathur, G., Napoli, Donna Jo, Padden, C., Rathmann, C., Smith, S.   +6 more
core   +2 more sources

Closed Abdominal Trauma with Isolated Gallbladder Injury

Неотложная медицинская помощь, 2020
Clinical observation of closed abdominal trauma and isolated gallbladder injury is discussed. The frequency of occurrence and risk factors for the development of gallbladder injury are presented.
S. E. Grigoriev, E. O. Inozemtsev, S. A. Kondratyev   +2 more
doaj   +1 more source

The ATIS sign language corpus [PDF]

, 2008
Systems that automatically process sign language rely on appropriate data. We therefore present the ATIS sign language corpus that is based on the domain of air travel information. It is available for five languages, English, German, Irish sign language,
Bungeroth, Jan, Dreuw, Philippe, Morrissey, Sara, Ney, Hermann, Stein, Daniel, van Zijl, Lynette, Way, Andy   +6 more
core  

Carcinomas and Carcinoid Tumors of the Lungs and Bronchi in Children and Adolescents: The EXPeRT Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Primary lung carcinomas and bronchial carcinoid tumors (BC) are very rare malignancies in childhood. While typical BC and mucoepidermoid carcinomas are mostly low‐grade, localized tumors with a more favorable prognosis than in adults, necessitating avoidance of overtreatment, adenocarcinomas of the lung are often diagnosed at advanced disease ...
Michael Abele, Calogero Virgone, Michaela Kuhlen, Sabine Irtan, Yves Reguerre, Malgorzata Krawczyk, Ewa Bien, Tal Ben‐Ami, Maja Cesen, Ricardo Lopez‐Almaraz, Andrea Ferrari, Gianni Bisogno, Dominik T. Schneider, Abbas Agaimy, Constantin Lapa, Hubert Ducou le Pointe, Rainer Claus, Catherine Daniel, Ines B. Brecht, Daniel Orbach   +19 more
wiley   +1 more source

Establishing a human bone marrow single cell reference atlas to study ageing and diseases

Frontiers in Immunology, 2023
IntroductionAgeing in the human bone marrow is associated with immune function decline that results in the elderly being vulnerable to illnesses. A comprehensive healthy bone marrow consensus atlas can serve as a reference to study the immunological ...
Nicole Yee Shin Lee, Mengwei Li, Kok Siong Ang, Jinmiao Chen, Jinmiao Chen   +4 more
doaj   +1 more source

Computational complexity and fundamental limitations to fermionic quantum Monte Carlo simulations

, 2004
Quantum Monte Carlo simulations, while being efficient for bosons, suffer from the "negative sign problem'' when applied to fermions - causing an exponential increase of the computing time with the number of particles.
E. Farhi, Matthias Troyer, S. Cook, Uwe-Jens Wiese   +3 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source