Results 31 to 40 of about 6,175,859 (338)

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

open access: yesNature Communications, 2018
Treg cells can maintain intestinal homeostasis and limit intestinal bowel disease. Here the authors use a mouse model of spontaneous colitis to show that calcineurin-NFAT-induced IL-2 production by dendritic cells regulates the balance between Treg and ...
Andrea Mencarelli   +12 more
doaj   +1 more source

A novel compartment, the 'subqpical stem' of the aerial hyphae, is the location of a sigN-dependent, developmentally distinct transcription in Streptomyces coelicolor. [PDF]

open access: yes, 2007
Streptomyces coelicolor has nine SigB-like RNA polymerase sigma factors, several of them implicated in morphological differentiation and/or responses to different stresses. One of the nine, SigN, is the focus of this article.
Bignell D.R.   +21 more
core   +1 more source

Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

open access: yesNature Communications, 2019
Severe malaria can be associated with respiratory complications. Here, the authors show that malaria-associated pulmonary vascular damage is a consequence of IFNγ-activated lung endothelial cells capturing, processing, and cross-presenting malaria ...
Carla Claser   +13 more
doaj   +1 more source

CD103+ Dendritic Cells Control Th17 Cell Function in the Lung

open access: yesCell Reports, 2015
Th17 cells express diverse functional programs while retaining their Th17 identity, in some cases exhibiting a stem-cell-like phenotype. Whereas the importance of Th17 cell regulation in autoimmune and infectious diseases is firmly established, the ...
Teresa Zelante   +14 more
doaj   +1 more source

Numeral Incorporation as Grammaticalization? A Corpus Study on German Sign Language (DGS)

open access: yesLanguages, 2023
Numeral incorporation describes the merging of a numeral sign with a lexical sign to create a single sign with a compositional meaning, e.g., “three weeks.” As a phenomenon of simultaneous morphology, numeral incorporation is unique to sign languages ...
Felicitas Otte   +3 more
doaj   +1 more source

Sign language recognition with transformer networks [PDF]

open access: yes, 2020
Sign languages are complex languages. Research into them is ongoing, supported by large video corpora of which only small parts are annotated. Sign language recognition can be used to speed up the annotation process of these corpora, in order to aid ...
Dambre, Joni   +2 more
core  

Toward solving the sign problem with path optimization method [PDF]

open access: yes, 2017
We propose a new approach to circumvent the sign problem in which the integration path is optimized to control the sign problem. We give a trial function specifying the integration path in the complex plane and tune it to optimize the cost function which
Kashiwa, Kouji   +2 more
core   +2 more sources

CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2

open access: yesbioRxiv, 2020
As the COVID-19 pandemic continues to spread, investigating the processes underlying the interactions between SARS-CoV-2 and its hosts is of high importance.
Razie Amraei   +17 more
semanticscholar   +1 more source

Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate

open access: yesEMBO Molecular Medicine, 2019
Currently, there are no commercially available live‐attenuated vaccines against chikungunya virus (CHIKV). Here, CHIKVs with mutations in non‐structural proteins (nsPs) were investigated for their suitability as attenuated CHIKV vaccines.
Yi‐Hao Chan   +15 more
doaj   +1 more source

Text2Sign: Towards Sign Language Production Using Neural Machine Translation and Generative Adversarial Networks

open access: yesInternational Journal of Computer Vision, 2020
We present a novel approach to automatic Sign Language Production using recent developments in Neural Machine Translation (NMT), Generative Adversarial Networks, and motion generation.
Stephanie Stoll   +3 more
semanticscholar   +1 more source

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