Results 21 to 30 of about 1,192,373 (315)
Mutating chikungunya virus non‐structural protein produces potent live‐attenuated vaccine candidate
EMBO Molecular Medicine, 2019 Currently, there are no commercially available live‐attenuated vaccines against chikungunya virus (CHIKV). Here, CHIKVs with mutations in non‐structural proteins (nsPs) were investigated for their suitability as attenuated CHIKV vaccines.
Yi‐Hao Chan +15 more
doaj +1 more source
Sign and Search: Sign Search Functionality for Sign Language Lexica
CoRR, 2021 Sign language lexica are a useful resource for researchers and people learning sign languages. Current implementations allow a user to search a sign either by its gloss or by selecting its primary features such as handshape and location. This study focuses on exploring a reverse search functionality where a user can sign a query sign in front of a ...
Fragkiadakis, M., Putten, P.W.H. van der
openaire +4 more sources
A Novel, Five-Marker Alternative to CD16–CD14 Gating to Identify the Three Human Monocyte Subsets
Frontiers in Immunology, 2019 Human primary monocytes are heterogeneous in terms of phenotype and function, but are sub-divided only based on CD16 and CD14 expression. CD16 expression distinguishes a subset of monocytes with highly pro-inflammatory properties from non-CD16 expressing
Siew-Min Ong +12 more
doaj +1 more source
RULES FOR ESTONIAN SIGN LANGUAGE TRANSCRIPTION; pp. 401–424 [PDF]
Trames, 2009 Estonian Sign Language (ESL) is the native language for approximately 1,500 Estonian dDeaf people. Like other sign languages, ESL has no written form. In the history of ESL research, different transcription systems have been used.
Regina Paabo +2 more
doaj +1 more source
Variation in Indonesian Sign Language
, 2019 This pioneering work on Indonesian Sign Language (BISINDO) explores the linguistic and social factors that lie behind variation in the grammatical domains of negation and completion.
Palfreyman, Nick
core +1 more source
EMBO Molecular Medicine, 2014 RNA‐sensing toll‐like receptors (TLRs) mediate innate immunity and regulate anti‐viral response. We show here that TLR3 regulates host immunity and the loss of TLR3 aggravates pathology in Chikungunya virus (CHIKV) infection.
Zhisheng Her +19 more
doaj +1 more source
Frontiers in Immunology, 2017 NLRP10 is a nucleotide-binding oligomerization domain-like receptor that functions as an intracellular pattern recognition receptor for microbial products.
Maurizio Vacca +21 more
doaj +1 more source
Immunological history governs human stem cell memory CD4 heterogeneity via the Wnt signaling pathway
Nature Communications, 2020 Aging is associated with immune attrition that may impact the effectiveness of the immune system to protect the host from pathogens. Here the authors show that immune aging is associated with alterations in the Wnt/β-catenin signaling and reduced stem ...
Hassen Kared +25 more
doaj +1 more source
iScience, 2021 Summary: The elderly are an important target for influenza vaccination, and the determination of factors that underlie immune responsiveness is clinically valuable.
Christophe Carre +17 more
doaj +1 more source
Frontiers in Immunology, 2019 The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis—a form of cell death induced by various pathogenic bacteria.
Hanif Javanmard Khameneh +11 more
doaj +1 more source