Results 21 to 30 of about 1,195,588 (315)
Publisher Correction: IgG1 memory B cells keep the memory of IgE responses
The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost labels ‘IgE spleen’ and ‘IgE BM’ incorrectly read ‘IgG1 spleen’ and ‘IgE1 BM’, respectively ...
Jin-Shu He +14 more
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Natural Selection: Sign, Sign, Everywhere a Sign [PDF]
Natural selection is an important factor influencing variation in the human genome, but most genetic studies of natural selection have focused on variants with unknown phenotypic associations. This trend is changing. New studies are rapidly revealing the effects of natural selection on genetic variants of known or likely functional importance.
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IgG1 memory B cells keep the memory of IgE responses
IgE is an important mediator of protective immunity as well as allergic reaction, but how high affinity IgE antibodies are produced in memory responses is not clear.
Jin-Shu He +14 more
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An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Carla Claser +13 more
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Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01
Allopurinol, widely used in gout treatment, is the most common cause of severe cutaneous adverse drug reactions. The risk of developing such life-threatening reactions is increased particularly for HLA-B*58:01 positive individuals.
Xuelu Huan +3 more
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Treg cells can maintain intestinal homeostasis and limit intestinal bowel disease. Here the authors use a mouse model of spontaneous colitis to show that calcineurin-NFAT-induced IL-2 production by dendritic cells regulates the balance between Treg and ...
Andrea Mencarelli +12 more
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On sign-symmetric signed graphs
A signed graph is said to be sign-symmetric if it is switching isomorphic to its negation. Bipartite signed graphs are trivially sign-symmetric. We give new constructions of non-bipartite sign-symmetric signed graphs. Sign-symmetric signed graphs have a symmetric spectrum but not the other way around.
Ebrahim Ghorbani +3 more
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Severe malaria can be associated with respiratory complications. Here, the authors show that malaria-associated pulmonary vascular damage is a consequence of IFNγ-activated lung endothelial cells capturing, processing, and cross-presenting malaria ...
Carla Claser +13 more
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Using a new effective action predicted from quantum gravity where the sign of the Euclidean Einstein action is reversed, we discuss Wentzel–Kramers–Brillouin (WKB) solutions in quantum cosmology and predict that this sign change might explain the origin of phantom scalars.
Arundhati Dasgupta, Adamantia Zampeli
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Sign and Search: Sign Search Functionality for Sign Language Lexica
Sign language lexica are a useful resource for researchers and people learning sign languages. Current implementations allow a user to search a sign either by its gloss or by selecting its primary features such as handshape and location. This study focuses on exploring a reverse search functionality where a user can sign a query sign in front of a ...
Fragkiadakis, M., Putten, P.W.H. van der
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