Results 31 to 40 of about 1,373,326 (296)
Frontiers in Immunology, 2019 The inflammasome is a multi-protein complex that mediates proteolytic cleavage and release of the pro-inflammatory cytokines IL-1β and IL-18, and pyroptosis—a form of cell death induced by various pathogenic bacteria.
Hanif Javanmard Khameneh +11 more
doaj +1 more source
iScience, 2021 Summary: The elderly are an important target for influenza vaccination, and the determination of factors that underlie immune responsiveness is clinically valuable.
Christophe Carre +17 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen +23 more
wiley +1 more source
Combining data-driven MT systems for improved sign language translation [PDF]
, 2007 In this paper, we investigate the feasibility of combining two data-driven machine translation (MT) systems for the translation of sign languages (SLs).
Morrissey, Sara +4 more
core +3 more sources
Closed Abdominal Trauma with Isolated Gallbladder Injury
Неотложная медицинская помощь, 2020 Clinical observation of closed abdominal trauma and isolated gallbladder injury is discussed. The frequency of occurrence and risk factors for the development of gallbladder injury are presented.
S. E. Grigoriev +2 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider +15 more
wiley +1 more source
Comparative Drug Response Profiling in Neuroblastoma Cell Lines and Patient‐Derived Tumor Organoids
Pediatric Blood &Cancer, EarlyView.ABSTRACT High‐risk neuroblastoma remains a leading cause of pediatric cancer mortality, and improved preclinical models are needed to guide therapeutic developments. We screened seven high‐risk neuroblastoma cell lines and three patient‐derived tumor organoids with 528 compounds alongside bone marrow controls, and compared them with external datasets ...
Krzysztof Wierbiłowicz +12 more
wiley +1 more source
Establishing a human bone marrow single cell reference atlas to study ageing and diseases
Frontiers in Immunology, 2023 IntroductionAgeing in the human bone marrow is associated with immune function decline that results in the elderly being vulnerable to illnesses. A comprehensive healthy bone marrow consensus atlas can serve as a reference to study the immunological ...
Nicole Yee Shin Lee +4 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Allogeneic hematopoietic stem cell transplantation (alloHSCT) is an essential therapy for several malignant and nonmalignant diseases, but relapse and graft loss remain the principal threats to its success. Routine monitoring of chimerism and minimal residual disease (MRD) enables early detection of imminent recurrence and guides ...
Carmen Junk +10 more
wiley +1 more source
Frontiers in Immunology, 2013 Despite increasing studies targeted at host-pathogen interactions, vector-borne diseases remain one of the largest economic health burdens worldwide. Such diseases are vectored by hematophagous arthropods that deposit pathogens into the vertebrate host’s
Shu Zhen eChong +3 more
doaj +1 more source