Results 11 to 20 of about 1,192,373 (315)
Natural Selection: Sign, Sign, Everywhere a Sign [PDF]
Current Biology, 2004 Natural selection is an important factor influencing variation in the human genome, but most genetic studies of natural selection have focused on variants with unknown phenotypic associations. This trend is changing. New studies are rapidly revealing the effects of natural selection on genetic variants of known or likely functional importance.
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IgG1 memory B cells keep the memory of IgE responses
Nature Communications, 2017 IgE is an important mediator of protective immunity as well as allergic reaction, but how high affinity IgE antibodies are produced in memory responses is not clear.
Jin-Shu He +14 more
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Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01
Scientific Reports, 2023 Allopurinol, widely used in gout treatment, is the most common cause of severe cutaneous adverse drug reactions. The risk of developing such life-threatening reactions is increased particularly for HLA-B*58:01 positive individuals.
Xuelu Huan +3 more
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Nature Communications, 2019 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Carla Claser +13 more
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Nature Communications, 2018 Treg cells can maintain intestinal homeostasis and limit intestinal bowel disease. Here the authors use a mouse model of spontaneous colitis to show that calcineurin-NFAT-induced IL-2 production by dendritic cells regulates the balance between Treg and ...
Andrea Mencarelli +12 more
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On sign-symmetric signed graphs
Ars Mathematica Contemporanea, 2020 A signed graph is said to be sign-symmetric if it is switching isomorphic to its negation. Bipartite signed graphs are trivially sign-symmetric. We give new constructions of non-bipartite sign-symmetric signed graphs. Sign-symmetric signed graphs have a symmetric spectrum but not the other way around.
Ebrahim Ghorbani +3 more
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Nature Communications, 2019 Severe malaria can be associated with respiratory complications. Here, the authors show that malaria-associated pulmonary vascular damage is a consequence of IFNγ-activated lung endothelial cells capturing, processing, and cross-presenting malaria ...
Carla Claser +13 more
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CD103+ Dendritic Cells Control Th17 Cell Function in the Lung
Cell Reports, 2015 Th17 cells express diverse functional programs while retaining their Th17 identity, in some cases exhibiting a stem-cell-like phenotype. Whereas the importance of Th17 cell regulation in autoimmune and infectious diseases is firmly established, the ...
Teresa Zelante +14 more
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Numeral Incorporation as Grammaticalization? A Corpus Study on German Sign Language (DGS)
Languages, 2023 Numeral incorporation describes the merging of a numeral sign with a lexical sign to create a single sign with a compositional meaning, e.g., “three weeks.” As a phenomenon of simultaneous morphology, numeral incorporation is unique to sign languages ...
Felicitas Otte +3 more
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International Journal of Modern Physics D, 2012 Using a new effective action predicted from quantum gravity where the sign of the Euclidean Einstein action is reversed, we discuss Wentzel–Kramers–Brillouin (WKB) solutions in quantum cosmology and predict that this sign change might explain the origin of phantom scalars.
Dasgupta, Arundhati, Zampeli, Adamantia
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