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Réflexions sur la formalisation, en tant que système, d’une transcription des formes des Langues des Signes : l’approche Typannot [PDF]

open access: yesSHS Web of Conferences, 2020
Transcrire les langues des signes (LS) nécessite de prendre en considération leur nature gestuelle et de comprendre les raisons (parmi lesquelles centration sur les mains et utilisation d’un cadre de référence égocentré) pour lesquelles des systèmes ...
Boutet Dominique   +9 more
doaj   +1 more source

Analysis of archaic human haplotypes suggests that 5hmC acts as an epigenetic guide for NCO recombination

open access: yesBMC Biology, 2022
Background Non-crossover (NCO) refers to a mechanism of homologous recombination in which short tracks of DNA are copied between homologue chromatids.
Bernett Lee   +6 more
doaj   +1 more source

Gut-Evolved Candida albicans Induces Metabolic Changes in Neutrophils

open access: yesFrontiers in Cellular and Infection Microbiology, 2021
Serial passaging of the human fungal pathogen Candida albicans in the gastrointestinal tract of antibiotics-treated mice selects for virulence-attenuated strains.
Jose Antonio Reales-Calderon   +9 more
doaj   +1 more source

FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression

open access: yesCommunications Biology, 2021
Puan and San Luis et al. find that FUT6, encoding a fucosyltransferase, is required for the “rolling” behavior of certain white blood cells that enables them to move from blood vessels to tissues.
Kia Joo Puan   +19 more
doaj   +1 more source

A benchmark of batch-effect correction methods for single-cell RNA sequencing data

open access: yesGenome Biology, 2020
Background Large-scale single-cell transcriptomic datasets generated using different technologies contain batch-specific systematic variations that present a challenge to batch-effect removal and data integration.
Hoa Thi Nhu Tran   +6 more
doaj   +1 more source

Publisher Correction: IgG1 memory B cells keep the memory of IgE responses

open access: yesNature Communications, 2018
The originally published version of this Article contained errors in Fig. 4 that were introduced during the production process. In panel c, the two uppermost labels ‘IgE spleen’ and ‘IgE BM’ incorrectly read ‘IgG1 spleen’ and ‘IgE1 BM’, respectively ...
Jin-Shu He   +14 more
doaj   +1 more source

IgG1 memory B cells keep the memory of IgE responses

open access: yesNature Communications, 2017
IgE is an important mediator of protective immunity as well as allergic reaction, but how high affinity IgE antibodies are produced in memory responses is not clear.
Jin-Shu He   +14 more
doaj   +1 more source

Author Correction: Lung endothelial cell antigen cross-presentation to CD8+T cells drives malaria-associated lung injury

open access: yesNature Communications, 2019
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Carla Claser   +13 more
doaj   +1 more source

Allopurinol non-covalently facilitates binding of unconventional peptides to HLA-B*58:01

open access: yesScientific Reports, 2023
Allopurinol, widely used in gout treatment, is the most common cause of severe cutaneous adverse drug reactions. The risk of developing such life-threatening reactions is increased particularly for HLA-B*58:01 positive individuals.
Xuelu Huan   +3 more
doaj   +1 more source

Calcineurin-mediated IL-2 production by CD11chighMHCII+ myeloid cells is crucial for intestinal immune homeostasis

open access: yesNature Communications, 2018
Treg cells can maintain intestinal homeostasis and limit intestinal bowel disease. Here the authors use a mouse model of spontaneous colitis to show that calcineurin-NFAT-induced IL-2 production by dendritic cells regulates the balance between Treg and ...
Andrea Mencarelli   +12 more
doaj   +1 more source

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