Results 71 to 80 of about 7,799 (146)

Influence of MC1R Gene Variants on Coat Color of Indicine Cattle Breeds

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT Indicine cattle display a broad range of coat colors, representing a relevant and breed‐defining trait required for registration in breeder association. Among the genes involved in pigmentation, MC1R stands out for modulating the synthesis of melanin‐related proteins and remains poorly explored in indicine cattle breeds. Therefore, we aimed to
Silel V. S. A. Maciel, Ingrid P. P. Oliveira, Beatriz B. Senes, Carolaine J. S. Santana, Jackeline S. Alves, Edilane A. da Silva, Fernando O. Franco, Bárbara C. F. da Silva, Fernando C. Cairo, Frederico C. Cairo, Aníbal E. Vercesi‐Filho, Raphael B. Costa, Gregório M. F. de Camargo   +12 more
wiley   +1 more source

Reciprocal sign epistasis and sign epistasis may not be found in multi-peaked landscapes

Abstract Fitness landscapes is a mathematical framework for rigorously analyzing evolutionary dynamics including study of epistasis, the main obstacle to predicting phenotype from genotype. In 2011, Poelwijk et al. formulated a theorem asserting that in a multi-peaked fitness landscape, “at least two mutations exhibit reciprocal sign ...
Dmitry N. Ivankov, Evgenii M. Zorin
openaire   +1 more source

RNA binding protein ZFP36L1 promotes ferroptosis in chronic rhinosinusitis by destabilizing CAMK2A mRNA and impairing mitochondrial quality control

Clinical and Translational Medicine, Volume 16, Issue 5, May 2026.
This graphical abstract illustrates the novel ZFP36L1–CAMK2A regulatory axis in chronic rhinosinusitis (CRS) pathogenesis: 1. Molecular initiation: In nasal epithelial cells, the RNA‐binding protein ZFP36L1 (upregulated in CRS) directly binds to AU‐rich elements (AREs) in the 3′‐untranslated region (3′‐UTR) of CAMK2A mRNA, promoting its degradation and
Jiayi Xiong, Shihan Zhang, Chunhua Li, Yufeng Ai, Xinru Liu, Yuxiang Liu, Hongbing Liu   +6 more
wiley   +1 more source

Repeatability of evolution on epistatic landscapes

, 2015
Evolution is a dynamic process. The two classical forces of evolution are mutation and selection. Assuming small mutation rates, evolution can be predicted based solely on the fitness differences between phenotypes.
Bauer, Benedikt, Gokhale, Chaitanya S.
core   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, Volume 13, Issue 19, 2 April 2026.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

Combining Ability and Gene Action Estimates of Eight Parent Diallel Crosses of Chickpea for Ascochyta Blight

Advances in Agriculture, 2015
Ascochyta blight resistance was studied in half-diallel cross involving eight genotypes of chickpea at seedling and adult stages. The disease was rated in the greenhouse with a modified scale from 0 to 100%.
Mohamed Labdi, Samia Ghomari, Samia Hamdi   +2 more
doaj   +1 more source

Genome‐wide associations of leaf spectral variation in MAGIC lines of Nicotiana attenuata

Ecology, Volume 107, Issue 4, April 2026.
Abstract The application of in‐field and aerial spectroscopy to assess functional and phylogenetic variation in plants has led to novel ecological insights and supports global assessments of plant biodiversity. Understanding how plant genetic variation influences reflectance spectra will help harness this potential for biodiversity monitoring and ...
Cheng Li, Ewa A. Czyż, Bernhard Schmid, Rishav Ray, Rayko Halitschke, Ian T. Baldwin, Michael E. Schaepman, Meredith C. Schuman   +7 more
wiley   +1 more source

Mutation supply and the repeatability of selection for antibiotic resistance

, 2017
Whether evolution can be predicted is a key question in evolutionary biology. Here we set out to better understand the repeatability of evolution. We explored experimentally the effect of mutation supply and the strength of selective pressure on the ...
de Visser, J. Arjan G. M., Hwang, Sungmin, Krug, Joachim, van Dijk, Thomas, Zwart, Mark P.   +4 more
core   +1 more source

A century of theories of balancing selection

Biological Reviews, Volume 101, Issue 2, Page 804-825, April 2026.
ABSTRACT Traits that affect organismal fitness are often highly genetically variable. This genetic variation is vital for populations to adapt to their environments, but it is also surprising given that nature – after all – ‘selects’ the best genotypes at the expense of those that fall short.
Filip Ruzicka, Martyna K. Zwoinska, Debora Goedert, Hanna Kokko, Xiang‐Yi Li Richter, Iain R. Moodie, Sofie Nilén, Colin Olito, Erik I. Svensson, Peter Czuppon, Tim Connallon   +10 more
wiley   +1 more source

Multiple-line inference of selection on quantitative traits

, 2015
Trait differences between species may be attributable to natural selection. However, quantifying the strength of evidence for selection acting on a particular trait is a difficult task.
Berg, Johannes, Khatri, Bhavin S., Lässig, Michael, Riedel, Nico   +3 more
core   +1 more source