Results 91 to 100 of about 35,633 (306)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Object marking in German Sign Language (Deutsche Gebärdensprache): Differential object marking and object shift in the visual modality

open access: yesGlossa, 2020
This article discusses differential object marking and object shift in German Sign Language (DGS). Although there is already some literature discussing the existence of differential object marking in sign languages, this article provides the first in ...
Fabian Bross
doaj   +2 more sources

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Building a sign language corpus for use in machine translation [PDF]

open access: yes, 2010
In recent years data-driven methods of machine translation (MT) have overtaken rule-based approaches as the predominant means of automatically translating between languages.
Harold Somers   +9 more
core  

Visual prosody in Korean Sign Language: (non)manual cues for boundary and prominence

open access: yesFrontiers in Psychology
IntroductionThis study examines how manual and nonmanual features contribute to prosodic marking in Korean Sign Language (KSL), particularly for prominence and Accentual Phrase (AP) boundaries.
Jungah Lee, Youngju Choi
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Sign languages in Jamaica [PDF]

open access: yes, 1986
Two different sign languages are in use by deaf persons in Jamaica. The "urban" variation is very similar to varieties of signing used in the US, while the "rural" or "country" sign language is marked by use of physical portrayals and emphasis on ...
Dolman, David
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Interrogative and Negative Constructions in Sign Language [PDF]

open access: yes, 2006
THE FIRST VOLUME IN THE SIGN LANGUAGE TYPOLOGY SERIES includes data on interrogative and negative constructions from 35 sign languages around the world.
Zeshan, Ulrike
core   +1 more source

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