Results 81 to 90 of about 35,493 (306)

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Semantic Fields in Sign Languages. Colour, Kinship and Quantification

open access: yes, 2016
This book presents primary data and typological comparisons across sign languages with respect to three semantic fields: kinship terms, colour terms and quantification.
Zeshan, Ulrike, Sagara, Keiko
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi   +2 more
wiley   +1 more source

Object marking in German Sign Language (Deutsche Gebärdensprache): Differential object marking and object shift in the visual modality

open access: yesGlossa, 2020
This article discusses differential object marking and object shift in German Sign Language (DGS). Although there is already some literature discussing the existence of differential object marking in sign languages, this article provides the first in ...
Fabian Bross
doaj   +2 more sources

Building a sign language corpus for use in machine translation [PDF]

open access: yes, 2010
In recent years data-driven methods of machine translation (MT) have overtaken rule-based approaches as the predominant means of automatically translating between languages.
Harold Somers   +9 more
core  

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel   +8 more
wiley   +1 more source

Visual prosody in Korean Sign Language: (non)manual cues for boundary and prominence

open access: yesFrontiers in Psychology
IntroductionThis study examines how manual and nonmanual features contribute to prosodic marking in Korean Sign Language (KSL), particularly for prominence and Accentual Phrase (AP) boundaries.
Jungah Lee, Youngju Choi
doaj   +1 more source

On Relativization and Clefting. An Analysis of Italian Sign Language

open access: yes, 2015
This work is a contribution to our understanding of relativization strategies and clefting in Italian Sign Language, and more broadly, to our understanding of these constructions in world languages by setting the discussion on the theories that have been
Branchini, Chiara
core   +1 more source

Arandic alternate sign language(s)

open access: yes, 2020
This chapter describes sign language(s) used in Arandic language speaking communities of Central Australia. These sign languages have been called ‘alternate’ because they are not usually the primary mode of communication, but rather employed alongside ...
Green, Jennifer, Wilkins, David P
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

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