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Integration of Innate Immune Signaling
Trends in Immunology, 2016The last decades of research in innate immunology have revealed a multitude of sensing receptors that evaluate the presence of microorganisms or cellular damage in tissues. In the context of a complex tissue, many such sensing events occur simultaneously. Thus, the downstream pathways need to be integrated to launch an appropriate cellular response, to
Christoph A, Thaiss +3 more
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Integrin signaling is integral to regeneration
Experimental Neurology, 2008The inability of the adult injured mammalian spinal cord to successfully regenerate is not well understood. Studies suggest that both extrinsic and intrinsic factors contribute to regeneration failure. In this review, we focus on intrinsic factors that impact regeneration, in particular integrin receptors and their downstream signaling pathways.
Michele L, Lemons, Maureen L, Condic
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Integrating signals in stomatal development
Current Opinion in Plant Biology, 2004Stomata are specialized epidermal structures that control the exchange of water and carbon dioxide between the plant and the atmosphere. The classical developmental mechanisms that define cell fate and tissue patterning - cell lineage, cell-cell interactions and signals from a distance - are employed to make stomata and to define their density and ...
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An integrating averager of microspectrofluorometric signals
Brain Research Bulletin, 1989Optical signals are used to measure a variety of cell events; in particular, ratiometric fluorescent dyes offer diverse applications, but bring with them the difficult analytical problem of obtaining optical signals at rapidly alternating wavelengths. An improved method for using a computer to record these optical signals is described, and an example ...
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Science's STKE, 2001
The vital role of interferons (IFNs) as mediators of innate immunity is well established. It has recently become apparent that one of the pivotal proteins in mediating the antiviral activity of IFNs, the double-stranded RNA (dsRNA)-activated protein kinase (PKR), also functions as a signal transducer in the proinflammatory response to ...
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The vital role of interferons (IFNs) as mediators of innate immunity is well established. It has recently become apparent that one of the pivotal proteins in mediating the antiviral activity of IFNs, the double-stranded RNA (dsRNA)-activated protein kinase (PKR), also functions as a signal transducer in the proinflammatory response to ...
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Signal Integrity and Power Integrity
IEEE Electromagnetic Compatibility Magazine, 2022openaire +1 more source